Search - Architecture et Fonction des Macromolécules Biologiques Access content directly

Filter your results

1 002 Results
Image document

Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration

Phong Quoc Nguyen , Sonia Huecas , Amna Asif-Laidin , Adrián Plaza-Pegueroles , Beatrice Capuzzi et al.
Nature Communications, 2023, 14 (1), pp.1729. ⟨10.1038/s41467-023-37109-4⟩
Journal articles hal-04056067v1

Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

Ashleigh Shannon , Véronique Fattorini , Bhawna Sama , Barbara Selisko , Mikael Feracci et al.
Preprints, Working Papers, ... hal-04061889v1

An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity

Richard Miallot , Virginie Millet , Yann Groult , Angelika Modelska , Lydie Crescence et al.
Life Science Alliance, 2023, 6, ⟨10.26508/lsa.202201767⟩
Journal articles hal-04066238v1

A subfamily classification to choreograph the diverse activities within glycoside hydrolase family 31

Thimali Arumapperuma , Jinling Li , Bastian Hornung , Niccolay Madiedo Soler , Ethan Goddard-Borger et al.
Journal of Biological Chemistry, 2023, 299 (4), pp.103038. ⟨10.1016/j.jbc.2023.103038⟩
Journal articles hal-04070174v1

Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores

Rhian Jones , Michael Hons , Nadia Rabah , Noelia Zamarreño , Rocío Arranz et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (12), ⟨10.1073/pnas.2213934120⟩
Journal articles hal-04041008v1
Image document

Interplay of RNA 2′-O-methylations with viral replication

Alice Decombe , Priscila El Kazzi , Etienne Decroly
Current Opinion in Virology, 2023, 59 (avril), pp.101302. ⟨10.1016/j.coviro.2023.101302⟩
Journal articles hal-03981798v1
Image document

Report from the 28th Meeting on Toxinology, “Toxins: What’s up, Doc?”, Organized by the French Society of Toxinology on 28–29 November 2022

P. Marchot , Évelyne Benoit , Ziad Fajloun , Sylvie Diochot
Toxins, 2023, 15, pp.126. ⟨10.3390/toxins15020126⟩
Journal articles hal-03978955v1
Image document

Guidelines for the Simulations of Nitroxide X-Band cw EPR Spectra from Site-Directed Spin Labeling Experiments Using SimLabel

Emilien Etienne , Annalisa Pierro , Ketty C Tamburrini , Alessio Bonucci , Elisabetta Mileo et al.
Molecules, 2023, 28 (3), pp.1348. ⟨10.3390/molecules28031348⟩
Journal articles hal-03971418v1
Image document

Biochemistry of the Respiratory Syncytial Virus L Protein Embedding RNA Polymerase and Capping Activities

Priscila Sutto-Ortiz , Jean-François Eléouët , François Ferron , Etienne Decroly
Viruses, 2023, 15 (2), pp.341. ⟨10.3390/v15020341⟩
Journal articles hal-03981809v1
Image document

Liaisons dangereuses: Intrinsic Disorder in Cellular Proteins Recruited to Viral Infection-Related Biocondensates

Greta Bianchi , Stefania Brocca , Sonia Longhi , Vladimir N Uversky
International Journal of Molecular Sciences, 2023, 24 (3), pp.2151. ⟨10.3390/ijms24032151⟩
Journal articles hal-03952115v1

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors

Haitham Hassan , Jeanne Chiavaralli , Afnan Hassan , Loay Bedda , Tim Krischuns et al.
RSC Medicinal Chemistry, 2023, 14 (3), pp.507-519. ⟨10.1039/D2MD00149G⟩
Journal articles hal-03981817v1

Amino Acid Polymorphisms on the Brazilian Strain of Yellow Fever Virus Methyltransferase Are Related to the Host’s Immune Evasion Mediated by Type I Interferon

Nathália Dias Furtado , Iasmim Silva de Mello , Andre Schutzer de Godoy , Gabriela Dias Noske , Glaucius Oliva et al.
Viruses, 2023, 15 (1), pp.191. ⟨10.3390/v15010191⟩
Journal articles hal-03981813v1
Image document

An HMM approach expands the landscape of sesquiterpene cyclases across the kingdom Fungi

Hayat Hage , Julie Couillaud , Asaf Salamov , Margot Loussouarn-Yvon , Fabien Durbesson et al.
Microbial Genomics, 2023, 9 (4), pp.000990. ⟨10.1099/mgen.0.000990⟩
Journal articles hal-04074453v1
Image document

Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases

Marcel Hausdorff , Adrien Delpal , Sarah Barelier , Laura Nicollet , Bruno Canard et al.
European Journal of Medicinal Chemistry, In press, ⟨10.1016/j.ejmech.2023.115474⟩
Journal articles hal-04095336v1
Image document

Conidium Specific Polysaccharides in Aspergillus fumigatus

Zhonghua Liu , Isabel Valsecchi , Rémy A Le Meur , Catherine Simenel , J. Iñaki Guijarro et al.
Journal of Fungi, 2023, 9 (2), pp.155. ⟨10.3390/jof9020155⟩
Journal articles pasteur-03988574v1
Image document

Toxins: what’s up, doc?

P. Marchot , Evelyne Benoit , Sylvie Diochot
Toxins, 15, , 2023, Special issue of Toxins
Special issue hal-03973916v1
Image document

Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies

Juliet F Nilsson , Hakima Baroudi , Frank Gondelaud , Giulia Pesce , Christophe Bignon et al.
International Journal of Molecular Sciences, 2022, 24 (1), pp.399. ⟨10.3390/ijms24010399⟩
Journal articles hal-03952101v1
Image document

In vitro Applications of the Terpene Mini‐Path 2.0

Julie Couillaud , Agnès Amouric , Elise Courvoisier‐dezord , Létitia Leydet , Nicolas Schweitzer et al.
ChemBioChem, 2022, 23 (24), pp.e202200595. ⟨10.1002/cbic.202200595⟩
Journal articles hal-03935973v1

Membrane-remodeling protein ESCRT-III homologs incarnate the evolution and morphogenesis of multicellular magnetotactic bacteria

Wenyan Zhang , Jianwei Chen , Jie Dai , Shiwei Zhu , Hugo Le Guenno et al.
Preprints, Working Papers, ... hal-03894042v1

Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides

Lucelia Cabral , Gabriela Persinoti , Douglas Paixão , Marcele Martins , Mariana Morais et al.
Nature Communications, 2022, 13 (1), pp.629. ⟨10.1038/s41467-022-28310-y⟩
Journal articles hal-03589026v1
Image document

SARS-CoV-2 detection using a nanobody-functionalized voltammetric device

Quentin Pagneux , Alain Roussel , Hiba Saada , Christian Cambillau , Béatrice Amigues et al.
Communications Medicine, 2022, 2 (1), pp.56. ⟨10.1038/s43856-022-00113-8⟩
Journal articles hal-03681653v1
Image document

Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect

Priscila El Kazzi , Nadia Rabah , Célia Chamontin , Lina Poulain , François Ferron et al.
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac996⟩
Journal articles hal-03860650v1
Image document

Diversity of genomic adaptations to the post‐fire environment in Pezizales fungi points to crosstalk between charcoal tolerance and sexual development

Andrei Steindorff , Kyungyong Seong , Akiko Carver , Sara Calhoun , Monika Fischer et al.
New Phytologist, 2022, 236 (3), pp.1154-1167. ⟨10.1111/nph.18407⟩
Journal articles hal-03992634v1
Image document

Split-GFP Reassembly Assay: Strengths and Caveats from a Multiparametric Analysis

Christophe Bignon , Antoine Gruet , Sonia Longhi
International Journal of Molecular Sciences, 2022, 23 (21), pp.13167. ⟨10.3390/ijms232113167⟩
Journal articles hal-03834586v1

Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans

Marcele Martins , Mariana Morais , Gabriela Persinoti , Rafael Galinari , Li Yu et al.
Acta crystallographica Section D : Structural biology [1993-..], 2022, 78 (11), pp.1358-1372. ⟨10.1107/S2059798322009561⟩
Journal articles hal-03982004v1

A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome

Ashleigh Shannon , Bhawna Sama , Pierre Gauffre , Théo Guez , Françoise Debart et al.
Nucleic Acids Research, 2022, 50 (19), pp.11186-11198. ⟨10.1093/nar/gkac876⟩
Journal articles hal-03937366v1
Image document

Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis

Sarah Barelier , Romain Avellan , Giri Raj Gnawali , Patrick Fourquet , Véronique Roig-Zamboni et al.
FEBS Journal, 2022, ⟨10.1111/febs.16645⟩
Journal articles hal-03799115v1

The long-awaited structure of human fucosidase FucA1 opens novel avenues for the treatment of fucosidosis

Sarah Barelier , Gerlind Sulzenbacher
Structure, 2022, 30 (10), pp.1369-1371. ⟨10.1016/j.str.2022.09.002⟩
Journal articles hal-03806314v1

Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses

Frank Gondelaud , Giulia Pesce , Juliet F. Nilsson , Christophe Bignon , Denis Ptchelkine et al.
Essays in Biochemistry, 2022, ⟨10.1042/EBC20220045⟩
Journal articles hal-03794799v1
Image document

Quantitative fragmentomics allow affinity mapping of interactomes

Gergo Gogl , Boglarka Zambo , Camille Kostmann , Alexandra Cousido-Siah , Bastien Morlet et al.
Nature Communications, 2022, 13 (1), pp.5472. ⟨10.1038/s41467-022-33018-0⟩
Journal articles hal-03843025v1