Cosmic rays are the only agent capable of ionizing the interior of dense molecular clouds and, thus, they are believed to play an essential role in determining the physical and chemical evolution of star-forming regions. In this work, we aim to study cosmic-ray induced ionization rates in starburst environments using non-thermal emissions of cosmic rays from starburst nuclei. To this end, we first revisit cosmic-ray models, which could explain data of non-thermal emissions from radio to X-ray and gamma-ray from nuclei of three prototypical starburst galaxies NGC 253, M82, and Arp 220. These models are then applied to predict ionization rates in starburst environments, which gives values around 10^−14 s^−1. Such a high value of the ionization rate, which is 2 to 3 orders of magnitude higher than the typical values found in the Milky Way, is probably due to relatively high rates of supernova explosions occurring within the nuclei of these starburst galaxies. We also discuss in more detail the case of NGC 253, where our predicted ionization rate is found to be, in most cases, a few times smaller than the values inferred from molecular line observations of clouds in the starburst nucleus. The general framework provided in this work illustrates how the use of non-thermal emission data could help to provide more insights into ionization rates or, more generally, cosmic-ray impact in starburst environments.