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Structure-based design of human immuno- and constitutive proteasomes inhibitors

N. Richy , D. Sarraf , X. Maréchal , N. Janmamode , E. Genin et al.
European Journal of Medicinal Chemistry, 2018, 145, pp.570-587. ⟨10.1016/j.ejmech.2018.01.013⟩
Journal articles hal-01713510v1
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Rôle du peptide amyloïde dans les maladies neurodégénératives

Maud Combes
Médecine humaine et pathologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS311⟩
Theses tel-02864804v1
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Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips

Benjamin Lassus , Jérémie Naudé , Philippe Faure , Denis Guedin , Ysander von Boxberg et al.
Scientific Reports, 2018, 8, pp.17461. ⟨10.1038/s41598-018-35802-9⟩
Journal articles hal-01943765v1
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Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness

Alexandra Bogeas , Ghislaine Morvan-Dubois , Elías El-Habr , François-Xavier Lejeune , Matthieu Defrance et al.
Acta Neuropathologica, 2018, 135 (2), pp.267-283. ⟨10.1007/s00401-017-1783-x⟩
Journal articles inserm-02368647v1
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Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts

Marine Le Boulch , Emad K Ahmed , Adelina Rogowska-Wrzesinska , Martín Baraibar , Bertrand Friguet et al.
Mechanisms of Ageing and Development, 2018, 170, pp.59-71. ⟨10.1016/j.mad.2017.07.005⟩
Journal articles hal-01787540v1
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Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training

Robin Deloux , Cynthia Tannous , Arnaud Ferry , Zhenlin Li , Mathias Mericskay et al.
Frontiers in Physiology, 2018, 9, pp.1290. ⟨10.3389/fphys.2018.01290⟩
Journal articles hal-01884625v1
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Importance de la protéase mitochondriale Lon dans le maintien de l'homéostasie protéique et de la fonction mitochondriale

Marie-Paule Hamon
Biologie cellulaire. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS241⟩
Theses tel-02476337v1
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Continuous performance test impairment in a 22q11.2 microdeletion mouse model: improvement by amphetamine

Simon R O Nilsson , Christopher J Heath , Samir Takillah , Steve Didienne , Kim Fejgin et al.
Translational Psychiatry, 2018, 8 (1), pp.247. ⟨10.1038/s41398-018-0295-3⟩
Journal articles hal-01924805v1
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Les peptides mimétiques de la Thiorédoxine-1 : nouvelle stratégie thérapeutique pour les maladies cardiovasculaires

Fanny Canesi
Médecine humaine et pathologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS500⟩
Theses tel-02613771v1
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Adaptations de la cascade de signalisation AMPc/PKA dans le striatum au cours de la maladie de Parkinson et de son traitement par la L-DOPA : étude par imagerie de biosenseurs sur un modèle animal

Cédric Yapo
Biologie cellulaire. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS603⟩
Theses tel-02901403v1
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Insights into the activity control of the kallikrein-related peptidase 6: small-molecule modulators and allosterism

Feryel Soualmia , Elodie Bosc , Sabrina Aït Amiri , Dirk Stratmann , Viktor Magdolen et al.
Biological Chemistry, 2018, 399, pp.1073 - 1078. ⟨10.1515/hsz-2017-0336⟩
Journal articles hal-03966511v1
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Novel short isoforms of adenylyl cyclase as negative regulators of cAMP production

Benjamin Vallin , Yohan Legueux-Cajgfinger , Nathalie Clement , Martine Glorian , Laurent Duca et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2018, 1865 (9), pp.1326-1340. ⟨10.1016/j.bbamcr.2018.06.012⟩
Journal articles hal-02372648v1
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Health-Related Quality of Life Is Severely Affected in Primary Orthostatic Tremor

Lucie Maugest , Eavan M Mcgovern , Katia Mazalovic , Mohamed Doulazmi , Emmanuelle Apartis et al.
Frontiers in Neurology, 2018, 8, pp.747. ⟨10.3389/fneur.2017.00747⟩
Journal articles hal-01700729v1
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Thery , Kenneth Witwer , Elena Aikawa , Maria Jose Alcaraz , Johnathon Anderson et al.
Journal of Extracellular Vesicles, 2018, 7 (1), pp.1535750. ⟨10.1080/20013078.2018.1535750⟩
Journal articles hal-02323217v1
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Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario

Charles Bou-Nader , Hugo Montémont , Vincent Guérineau , Olivier Jean-Jean , Damien Brégeon et al.
Nucleic Acids Research, 2018, 46 (3), pp.1386-1394. ⟨10.1093/nar/gkx1294⟩
Journal articles hal-01727508v1
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Dysregulated Neurotransmission induces Trans-synaptic degeneration in reconstructed Neuronal Networks

Bérangère Deleglise , Benjamin Lassus , Vanessa Soubeyre , Mohamed Doulazmi , Bernard Brugg et al.
Scientific Reports, 2018, 8, pp.11596. ⟨10.1038/s41598-018-29918-1⟩
Journal articles hal-01907549v1
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The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

Aurore L'Honoré , Pierre-Henri Commère , Elisa Negroni , Giorgia Pallafacchina , Bertrand Friguet et al.
eLife, 2018, 7, pp.e32991. ⟨10.7554/eLife.32991⟩
Journal articles hal-01908415v1
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Investigation of brain stimulation in animal models of depression and Alzheimer’s disease : feasibility of tailored treatments

Alesha Heath
Neurons and Cognition [q-bio.NC]. Sorbonne Université; University of Western Australia, 2018. English. ⟨NNT : 2018SORUS616⟩
Theses tel-03357857v1
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Analysis of the Genetic Diversity and Population Structure of Austrian and Belgian Wheat Germplasm within a Regional Context Based on DArT Markers

Mohamed A. El-Esawi , Jacques Witczak , Abd El-Fatah Abomohra , Hayssam M Ali , Mohamed S Elshikh et al.
Genes, 2018, 9 (1), pp.47. ⟨10.3390/genes9010047⟩
Journal articles hal-01717692v1
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Rôle de la Caspase-2 au cours des processus neurodégénératifs associés au vieillissement. Conception rationnelle d’inhibiteurs sélectifs et évaluation sur des modèles biologique

Elodie David-Bosc
Biochimie [q-bio.BM]. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS173⟩
Theses tel-02457149v1
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Study protocol on Alzheimer’s disease and related disorders: focus on clinical and imaging predictive markers in co-existing lesions

Nawèle Boublay , Denis Fédérico , Alain Pesce , Marc Verny , Frédéric Blanc et al.
BMC Geriatrics, 2018, 18 (1), pp.280. ⟨10.1186/s12877-018-0949-2⟩
Journal articles hal-01926463v1
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The role of integrin αv expressed by VSMCs in vascular fibrosis

Lei Tian
Cellular Biology. Sorbonne Université, 2018. English. ⟨NNT : 2018SORUS103⟩
Theses tel-02886136v1
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The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Sofia Lourenço dos Santos , Isabelle Petropoulos , Bertrand Friguet
Antioxidants , 2018, 7 (12), pp.191. ⟨10.3390/antiox7120191⟩
Journal articles hal-01982249v1
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Low-intensity electromagnetic fields induce human cryptochrome to modulate intracellular reactive oxygen species

Rachel M. Sherrard , Natalie Morellini , Nathalie Jourdan , Mohamed El-Esawi , Louis-David Arthaut et al.
PLoS Biology, 2018, 16 (10), pp.e2006229. ⟨10.1371/journal.pbio.2006229⟩
Journal articles hal-01946010v1
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Mechanisms involved in the cross-talk between humoral and mechanical cues underlying muscle wasting in cachexia

Alexandra Baccam
Tissues and Organs [q-bio.TO]. Sorbonne Université; Università degli studi La Sapienza (Rome), 2018. English. ⟨NNT : 2018SORUS107⟩
Theses tel-02345574v1