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Article Dans Une Revue Trends in Neurosciences Année : 2021

The Tail of the Striatum: From Anatomy to Connectivity and Function

Résumé

The dorsal striatum, the largest subcortical structure of the basal ganglia, is critical in controlling motor, procedural, and reinforcement-based behaviors. Although in mammals the striatum extends widely along the rostro-caudal axis, current knowledge and derived theories about its anatomo-functional organization largely rely on results obtained from studies of its rostral sectors, leading to potentially oversimplified working models of the striatum as a whole. Recent findings indicate that the extreme caudal part of the striatum, also referred to as the tail of striatum (TS), represents an additional functional domain. Here, we provide an overview of past and recent studies revealing that the TS displays a heterogeneous cell-type-specific organization, and a unique input-output connectivity, which poises the TS as an integrator of sensory processing.
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hal-03052590 , version 1 (10-03-2023)

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Paternité - Pas d'utilisation commerciale

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Emmanuel Valjent, Giuseppe Gangarossa. The Tail of the Striatum: From Anatomy to Connectivity and Function. Trends in Neurosciences, 2021, 44 (3), pp.203-214. ⟨10.1016/j.tins.2020.10.016⟩. ⟨hal-03052590⟩
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