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Article Dans Une Revue European Journal of Organic Chemistry Année : 2015

Suzuki–Miyaura Reactions of Halospirooxindole Derivatives.

Résumé

Starting from 5,5′-dihalo-1′-pentyl-2H-spiro[furo[2,3-b]pyridine-3,3′-indolin]-2′-one, various 5,5′-di(het)aryl-1′-pentyl-2H-spiro[furo[2,3-b]pyridine-3,3′-indolin]-2′-ones were synthesized through palladium-catalysed cross-coupling reactions. A large panel of boronic acids (aryl or heteroaryl) could easily be introduced, leading to a library of new 5- or 5′-monosubstituted and 5,5′-disubstituted 1′-pentyl-2H-spiro[furo[2,3-b]pyridine-3,3′-indolin]-2′-ones.

Domaines

Chimie

Dates et versions

hal-01213328 , version 1 (08-10-2015)

Identifiants

Citer

Abderrahman El Bouakher, Hassan Allouchi, Isabelle Abrunhosa-Thomas, Yves Troin, Gérald Guillaumet. Suzuki–Miyaura Reactions of Halospirooxindole Derivatives.. European Journal of Organic Chemistry, 2015, 2015 (16), pp.3450-3461. ⟨10.1002/ejoc.201500268⟩. ⟨hal-01213328⟩
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