HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz - Laboratoire des Interactions Plantes Microbes Environnement Accéder directement au contenu
Article Dans Une Revue AIDS. Official journal of the international AIDS Society Année : 2008

HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

Résumé

HLA typing, demographic and immunological risk factors for nevirapine and efavirenz reactions were studied in a French cohort of HIV patients. Cases with isolated rash were significantly associated with HLA-DRB1M01 allele. No liver toxicity was observed and no association was detected with the percentage of CD4 T-cells. This study suggests that HLA-DRB1M01 allele plays an important role in susceptibility to cutaneous reactions associated with nevirapine and efavirenz in HIV patients.
Fichier non déposé

Dates et versions

hal-02667073 , version 1 (31-05-2020)

Identifiants

  • HAL Id : hal-02667073 , version 1
  • PRODINRA : 27074
  • WOS : 000254247200015

Citer

Zulma Vitezica, Brigitte Milpied, Christine Lonjou, Nicolas Borot, Terence Niel Ledger, et al.. HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS. Official journal of the international AIDS Society, 2008, 22 (4), pp.540-541. ⟨hal-02667073⟩
9 Consultations
0 Téléchargements

Partager

Gmail Facebook X LinkedIn More