Discovering domestication mutations in cauliflower
Résumé
During the development of agriculture over the centuries, humans have selected plants with advantageous agronomic traits. Identifying mutations responsible for these characteristics would enhance our knowledge in agronomy and facilitate the neo-domestication of plants or the improvement of existing varieties. This project aims to identify mutations underlying the domestication of plants in
cabbages (Brassicaceae oleraceae systems). It will first focus on mutations responsible for deregulation of the genetic network responsible for the aborted flower in cauliflower. A population level pangenome was build to identify genetic variation in 373 Brassica oleracea accessions. Genotype-to-morphotypes association analysis and known floral development genes are used to extract candidates variants. These variants, in cis or trans regulatory elements, are further analyzed in silico to identify those that most likely disrupt the interaction between TFs and DNA to alter expression of floral developmental genes. Candidates causatives mutations will be validated experimentally. The approach will be apply to other traits in cabbages.
Domaines
Sciences du Vivant [q-bio]Origine | Fichiers produits par l'(les) auteur(s) |
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