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Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

Eliana Nachman , Anne S Wentink , Karine Madiona , Luc Bousset , Taxiarchis Katsinelos et al.
Journal of Biological Chemistry, 2020, 295, pp.9676 - 9690. ⟨10.1074/jbc.ra120.013478⟩
Journal articles cea-03881446v1
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Le métabolisme astrocytaire de la L-sérine et ses implications dans la maladie d'Alzheimer : une potentielle approche thérapeutique

Pierre-Antoine Vigneron
Neurobiologie. Université Paris-Saclay, 2020. Français. ⟨NNT : 2020UPASL016⟩
Theses tel-02976106v1
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Camélidés, anticorps à domaine unique et coronavirus

Bertrand Ridremont , Hubert Laude , Marc Dhenain , Jean Dupouy Camet
Bulletin de l'Académie Vétérinaire de France, 2020, ⟨10.4267/2042/70849⟩
Journal articles hal-03053187v1
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An automated open-source workflow for standards-compliant integration of small animal magnetic resonance imaging data

Horea-Ioan Ioanas , Markus Marks , Clément M Garin , Marc Dhenain , Mehmet Fatih Yanik et al.
Frontiers in Neuroinformatics, 2020, 14, ⟨10.3389/fninf.2020.00005⟩
Journal articles hal-03053204v1
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Revisiting double diffusion encoding MRS in the mouse brain at 11.7T: Which microstructural features are we sensitive to?

Mélissa Vincent , Marco Palombo , Julien Valette
Journal articles hal-02456824v1
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Modèles primates et innovations thérapeutiques contre les maladies du système nerveux central

Marc Dhenain
2020, pp.34-37
Other publications hal-03053181v1
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Neocortical morphometry in Huntington's disease: Indication of the coexistence of abnormal neurodevelopmental and neurodegenerative processes

Jean-François Mangin , Denis Rivière , Edouard Duchesnay , Yann Cointepas , Véronique Gaura et al.
Neuroimage-Clinical, 2020, 26, pp.102211. ⟨10.1016/j.nicl.2020.102211⟩
Journal articles hal-02521738v1
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Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

Joanes Grandjean , Carola Canella , Cynthia Anckaerts , Gülebru Ayranci , Salma Bougacha et al.
NeuroImage, 2020, 205, pp.116278. ⟨10.1016/j.neuroimage.2019.116278⟩
Journal articles hal-03447162v1
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Identification de nouvelles sondes moléculaires contre des biomarqueurs des maladies neurodégénératives

Alix Bouvier-Müller
Biologie moléculaire. Université Paris-Saclay, 2020. Français. ⟨NNT : 2020UPASL011⟩
Theses tel-03920277v1
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Prion Amyloid Polymorphs -The Tag Might Change It All

Luc Bousset , Nina Luckgei , Mehdi Kabani , Carole Gardiennet , Anne Schütz et al.
Frontiers in Molecular Biosciences, 2020, 7, pp.190. ⟨10.3389/fmolb.2020.00190⟩
Journal articles cea-02912510v1
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Induction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued from human brains

Anne-Sophie Herard , Fanny Petit , Charlotte Gary , Martine Guillermier , Susana Boluda et al.
Acta Neuropathologica Communications, 2020, 8 (1), ⟨10.1186/s40478-020-01081-7⟩
Journal articles hal-03052986v1
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Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates

Paul-Henri Prévot , Kevin Gehere , Fabrice Arcizet , Himanshu Akolkar , Mina A Khoei et al.
Nature Biomedical Engineering, 2020, 4 (2), pp.172-180. ⟨10.1038/s41551-019-0484-2⟩
Journal articles hal-02505613v1
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The intellectual disability protein Oligophrenin1 controls astrocyte morphology and migration

Laure-Elise Pillet , Noémie Cresto , Yoann Saillour , Grégory Ghézali , Alexis-Pierre Bemelmans et al.
Glia, 2020, Epub ahead of print. ⟨10.1002/glia.23801⟩
Journal articles inserm-02506646v1
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The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding

Josquin Courte , Luc Bousset , Ysander von Boxberg , Catherine Villard , Ronald Melki et al.
Scientific Reports, 2020, 10, pp.4895. ⟨10.1038/s41598-020-61757-x⟩
Journal articles cea-02511811v1
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Dipeptide Repeat derived from C9orf72 Hexanucleotide Expansions Forms Amyloids or natively unfolded structures in vitro

Laurent Brasseur , Audrey Coens , Jehan Waeytens , Ronald Melki , Luc Bousset et al.
Biochemical and Biophysical Research Communications, 2020, ⟨10.1016/j.bbrc.2020.03.108⟩
Journal articles cea-02529282v1
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Glucose availability dictates the export of the soluble and prion forms of Sup35p via periplasmic or extracellular vesicles

Mehdi Kabani , Marion Pilard , Ronald Melki
Molecular Microbiology, 2020, 114, pp.322 - 332. ⟨10.1111/mmi.14515⟩
Journal articles cea-02556526v1
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Spatially regularized parametric map reconstruction for fast magnetic resonance fingerprinting

Fabian Balsiger , Alain Jungo , Olivier Scheidegger , Pierre G. Carlier , Mauricio Reyes et al.
Medical Image Analysis, 2020, 64, pp.101741. ⟨10.1016/j.media.2020.101741⟩
Journal articles hal-03490848v1
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Les protéinopathies infectieuses de Parkinson et d’Alzheimer

R. Melki
Bulletin de l'Académie Nationale de Médecine, 2020, 204 (3), pp.224-231. ⟨10.1016/j.banm.2019.12.019⟩
Journal articles cea-02859853v1
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Effects of chronic masitinib treatment in APPPS1dE9 transgenic mice modeling Alzheimer’s disease

Tengfei Li , Elodie Martin , Yah-Se Abada , Céline Boucher , Aurélia Cès et al.
Journal of Alzheimer's Disease, 2020, 76 (4), pp.1339-1345. ⟨10.3233/jad-200466⟩
Journal articles hal-03035522v1
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rAAV-mediated cochlear gene therapy: Prospects and challenges for clinical application

Fabian Blanc , Michel Mondain , Alexis-Pierre Bemelmans , Corentin Affortit , Jean-Luc Puel et al.
Journal of Clinical Medicine, 2020, 9 (2), pp.589. ⟨10.3390/jcm9020589⟩
Journal articles hal-03521743v1
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Evaluation of the Dopaminergic System Using In Vivo PET Imaging and Post-Mortem Analyses in the Context of Mild Neurodegenerative and Neuroinflammatory PD Models

Pauline Roost
Neurobiology. Université Paris-Saclay, 2020. English. ⟨NNT : 2020UPASS086⟩
Theses tel-03702252v1
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Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease.

Océane Guillemaud , Kelly Ceyzériat , Thomas Saint-Georges , Karine Cambon , Fanny Petit et al.
Neurobiology of Aging, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
Journal articles cea-03023752v1
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Animal Functional Magnetic Resonance Imaging: Trends and Path Toward Standardization

Francesca Mandino , Domenic H Cerri , Clement M Garin , Milou Straathof , Geralda a F van Tilborg et al.
Frontiers in Neuroinformatics, 2020, 13, ⟨10.3389/fninf.2019.00078⟩
Journal articles hal-03053221v1
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Differential Membrane Binding and Seeding of Distinct $\alpha$-Synuclein Fibrillar Polymorphs

Amulya Nidhi Shrivastava , Luc Bousset , Marianne Renner , Virginie Redeker , Jimmy Savistchenko et al.
Biophysical Journal, In press, ⟨10.1016/j.bpj.2020.01.022⟩
Journal articles cea-02480815v1
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Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients

Florence Aeschlimann , Nassim Ait-Abdallah , Jean-David Albert , Didier Alcais , Yannick Allanore et al.
Annals of the Rheumatic Diseases, 2020, pp.annrheumdis-2020-218310. ⟨10.1136/annrheumdis-2020-218310⟩
Journal articles hal-03105409v1
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Clinical-grade production and safe delivery of human ESC derived RPE sheets in primates and rodents

Karim Ben M'Barek , Stephane Bertin , Elena Brazhnikova , Céline Jaillard , Walter Habeler et al.
Biomaterials, 2020, 230, pp.119603. ⟨10.1016/j.biomaterials.2019.119603⟩
Journal articles hal-02485645v1
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Lean regional muscle volume estimates using explanatory bioelectrical models in healthy subjects and patients with muscle wasting

Damien Bachasson , Alper Carras Ayaz , Jessie Mosso , Aurélie Canal , Jean-Marc Boisserie et al.
Journal of Cachexia, Sarcopenia and Muscle, 2020, 12 (1), pp.39-51. ⟨10.1002/jcsm.12656⟩
Journal articles hal-03146449v1
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PRIMA subretinal wireless photovoltaic microchip implantation in non-human primate and feline models

Mahiul M K Muqit , Jean Pierre Hubschman , Serge Picaud , Douglas B Mccreery , Jan C van Meurs et al.
PLoS ONE, 2020, 15 (4), pp.e0230713. ⟨10.1371/journal.pone.0230713⟩
Journal articles inserm-02543287v1
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Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease

Juliette Le Douce , Marianne Maugard , Julien Veran , Marco Matos , Pierrick Jégo et al.
Cell Metabolism, 2020, 31 (3), pp.503-517.e8. ⟨10.1016/j.cmet.2020.02.004⟩
Journal articles hal-02989009v2
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Effect of Alzheimer’s disease‐related β‐amyloid peptide conformations in transgenic mouse models of β‐amyloidosis

Marina Célestine , Muriel Jacquier‐sarlin , Eve Borel , Anne‐sophie Herard , Alain Buisson et al.
Alzheimer's & Dementia , 2020, 16 (S2), ⟨10.1002/alz.043415⟩
Journal articles hal-03453388v1