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Impact of $\alpha$-synuclein fibrillar strains and β-amyloid assemblies on mouse cortical neurons endo-lysosomal logistics

Qiao-Ling Chou , Ania Alik , François Marquier , Ronald Melki , François Treussart et al.
eNeuro, 2022, 9, pp.ENEURO.0227 - 21.2022. ⟨10.1523/eneuro.0227-21.2022⟩
Journal articles cea-03683734v1
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Disease mechanisms of multiple system atrophy: What a pParallel between the form of pasta and the alpha-synuclein assemblies involved in MSA and PD tells us

Ronald Melki
The Cerebellum, 2022, 2022, ⟨10.1007/s12311-022-01417-0⟩
Journal articles cea-03827567v1
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Sequential or simultaneous injection of preformed fibrils and AAV overexpression of alpha-synuclein are equipotent in producing relevant pathology and behavioral deficits

Matilde Negrini , Giuseppe Tomasello , Marcus Davidsson , Alexis Fenyi , Cécile Adant et al.
Journal of Parkinson's disease, 2022, 12, pp.1133 - 1153. ⟨10.3233/jpd-212555⟩
Journal articles cea-03683739v1
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Human pericytes degrade diverse α-synuclein aggregates

Birger Victor Dieriks , Blake Highet , Ania Alik , Tracy Bellande , Taylor J Stevenson et al.
PLoS ONE, 2022, 17 (11), pp.e0277658. ⟨10.1371/journal.pone.0277658⟩
Journal articles cea-03862437v1
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Étude du métabolisme énergétique in vivo par IRM-CEST du glucose

Yohann Mathieu-Daudé
Imagerie. Université Paris-Saclay, 2022. Français. ⟨NNT : 2022UPAST061⟩
Theses tel-03696869v1
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Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease

Elena Galea , Laura D Weinstock , Raquel Larramona-Arcas , Alyssa F Pybus , Lydia Giménez-Llort et al.
Neurobiology of Disease, 2022, 166, pp.105655. ⟨10.1016/j.nbd.2022.105655⟩
Journal articles cea-03872733v1
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Evaluation of Memantine in AAV-AD Rat: A Model of Late-Onset Alzheimer’s Disease Predementia

B. Souchet , M. Audrain , S. Alves , R. Fol , S. Tada et al.
The Journal of prevention of Alzheimer's disease, 2022, 9 (338–347), ⟨10.14283/jpad.2021.67⟩
Journal articles hal-03798156v1
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Exploring the protective role of GDF5 against skeletal muscle disuse atrophy

Chiara Noviello , Massiré Traoré , Bruno Cadot , Lucile Saillard , Béatrice Matot et al.
Myology Conference 2022, Sep 2022, Nice (FRANCE), France
Conference poster hal-04020141v1
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Astrocytes and neuropsychiatric symptoms in neurodegenerative diseases: Exploring the missing links

Lucile Ben Haim , Carole Escartin
Current Opinion in Neurobiology, 2022, 72, pp.63-71. ⟨10.1016/j.conb.2021.09.002⟩
Journal articles cea-03872715v1
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Modelling α-Synuclein Aggregation and Neurodegeneration with Fibril Seeds in Primary Cultures of Mouse Dopaminergic Neurons

Aurore Tourville , David Akbar , Olga Corti , Jochen Prehn , Ronald Melki et al.
Cells, 2022, 11 (10), pp.1640. ⟨10.3390/cells11101640⟩
Journal articles hal-03679039v1
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Pericytes take up and degrade $\alpha$-synuclein but succumb to apoptosis under cellular stress

Taylor J Stevenson , Rebecca H Johnson , Justin Rustenhoven , Zoe Woolf , Leon C D Smyth et al.
Scientific Reports, 2022, 12, ⟨10.1038/s41598-022-20261-0⟩
Journal articles cea-03827547v1
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A proteomic analysis indicates that oxidative stress is the common feature triggering antibiotic production in Streptomyces coelicolor and in the pptA mutant of Streptomyces lividans

Clara Lejeune , Laila Sago , David Cornu , Virginie Redeker , Marie-Jöelle Virolle et al.
Frontiers in Microbiology, 2022, 12, pp.813993. ⟨10.3389/fmicb.2021.813993⟩
Journal articles hal-03639305v1
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Modelling $\alpha$-synuclein aggregation and neurodegeneration with fibril seeds in primary cultures of mouse dopaminergic neurons

Aurore Tourville , David Akbar , Olga Corti , Jochen H. M. Prehn , Ronald Melki et al.
Cells, 2022, 11 (10), pp.1640. ⟨10.3390/cells11101640⟩
Journal articles cea-03683729v1
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Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications

Angelo Iannielli , Mirko Luoni , Serena Gea Giannelli , Rosangela Ferese , Gabriele Ordazzo et al.
Cell Death and Disease, 2022, 13, pp.881. ⟨10.1038/s41419-022-05330-6⟩
Journal articles cea-03827544v1
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C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

Paolo Marchi , Lara Marrone , Laurent Brasseur , Audrey Coens , Christopher Webster et al.
Life Science Alliance, 2022, 5 (9), pp.e202101276. ⟨10.26508/lsa.202101276⟩
Journal articles cea-03683732v1
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Assessing potential correlation between T 2 relaxation and diffusion of lactate in the mouse brain

Eloïse Mougel , Sophie Malaquin , Julien Valette
Magnetic Resonance in Medicine, 2022, ⟨10.1002/mrm.29395⟩
Journal articles hal-03745887v1
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Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics

Ehsan Dadgar-Kiani , Gregor Bieri , Ronald Melki , Aaron D. Gitler , Jin Hyung Lee et al.
Cell Reports, 2022, 41, pp.111631. ⟨10.1016/j.celrep.2022.111631⟩
Journal articles cea-03862418v1
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An evolutionary gap in primate default mode network organization

Clément M Garin , Yuki Hori , Stefan Everling , Christopher T Whitlow , Finnegan J Calabro et al.
Cell Reports, 2022, 39, ⟨10.1016/j.celrep.2022.110669⟩
Journal articles hal-03872781v1
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Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions

Francesca de Giorgi , Muhammed Bilal Abdul-Shukkoor , Marianna Kashyrina , Leslie-Ann Largitte , Francesco de Nuccio et al.
Biomolecules, 2022, 12 (3), pp.436. ⟨10.3390/biom12030436⟩
Journal articles hal-03628777v1
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Exploring the protective role of GDF5 against skeletal muscle disuse atrophy

Chiara Noviello , Sestina Falcone , Bruno Cadot , Lucile Saillard , Béatrice Matot et al.
Myology Conference 2022, Sep 2022, Nice (FRANCE), France
Conference poster hal-03994516v1
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Using spectrally-selective radiofrequency pulses to enhance lactate signal for diffusion-weighted MRS measurements in vivo

Eloïse Mougel , Sophie Malaquin , Mélissa Vincent , Julien Valette
Journal of Magnetic Resonance, 2022, 334, pp.107113. ⟨10.1016/j.jmr.2021.107113⟩
Journal articles hal-03495688v1
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Physiological synaptic activity and recognition memory require astroglial glutamine

Giselle Cheung , Danijela Bataveljic , Josien Visser , Naresh Kumar , Julien Moulard et al.
Nature Communications, 2022, 13 (1), pp.753. ⟨10.1038/s41467-022-28331-7⟩
Journal articles hal-03625240v1
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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway

Laurene Abjean , Lucile Ben Haim , Miriam Riquelme-Perez , Pauline Gipchtein , Céline Derbois et al.
Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac068/6550082⟩
Journal articles cea-03872742v1
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Astrocytes réactifs et maladies cérébrales

Yiannis Poulot-Becq-Giraudon , Maria-Angeles Carrillo-de Sauvage , Carole Escartin
médecine/sciences, 2022, 38 (10), pp.786-794. ⟨10.1051/medsci/2022104⟩
Journal articles hal-03811511v1
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Dissecting aggregation and seeding dynamics of $\alpha$-Syn polymorphs using the phasor approach to FLIM

Jessica Tittelmeier , Silke Druffel-Augustin , Ania Alik , Ronald Melki , Carmen Nussbaum-Krammer et al.
Communications Biology, 2022, 5, pp.1345. ⟨10.1038/s42003-022-04289-6⟩
Journal articles cea-03907348v1
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Amyloid polymorphs and pathological diversities

Ronald Melki
Neurochemistry International, 2022, 156, ⟨10.1016/j.neuint.2022.105335⟩
Journal articles cea-03683748v1