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Article Dans Une Revue Physical Review E : Statistical, Nonlinear, and Soft Matter Physics Année : 2004

Base-sequence-dependent sliding of proteins on DNA

Résumé

The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered. Referring to the case of the T7 RNA-polymerase, we show that the protein should follow a noise-influenced sequence-dependent motion which deviate from the standard random walk usually assumed. The general validity and the implications of the results are discussed.

Dates et versions

hal-00003424 , version 1 (30-11-2004)

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Maria Barbi, Christophe Place, Vladislav Popkov, Mario Salerno. Base-sequence-dependent sliding of proteins on DNA. Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, 2004, 70, pp.041901. ⟨hal-00003424⟩
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