Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Mech Dev Année : 2002

Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system.

Résumé

The expression pattern of Lmx1a, a LIM-homeodomain gene disrupted in the dreher mouse neurological mutant, is described during development. Lmx1a is predominantly expressed in the developing nervous system from embryonic day E8.5 to adulthood, in restricted areas. Major expression domains include the dorsal midline (roof plate) of the neural tube, the cortical hem, the otic vesicles, the developing cerebellum and the notochord. The Lmx1a expression pattern is therefore well correlated with the various aspects of the phenotype of the dreher mutant mice.
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Dates et versions

hal-00122205 , version 1 (28-12-2006)

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Vieri Failli, Isabelle Bachy, Sylvie Rétaux. Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system.. Mech Dev, 2002, 118 (1-2), pp.225-8. ⟨10.1016/S0925-4773(02)00254-X⟩. ⟨hal-00122205⟩

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