Reactions of N,N-diisopropyl-2-aminoethylp-fluorobenzene thiosulfonate with oxidising agents - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Comptes rendus de l’Académie des sciences. Série IIc, Chimie Année : 2001

Reactions of N,N-diisopropyl-2-aminoethylp-fluorobenzene thiosulfonate with oxidising agents

Résumé

The behaviour of N,N-diisopropyl-2-aminoethyl p-fluorobenzene thiosulfonate 3, which may be considered as a weakly toxic chemical analogue of VX agent, was investigated against oxidising agents. As VX 1, this compound exhibits the same tendency to give S–S bond cleavage. Its degradation by Curox® shows the formation of the N-oxide 6 which subsequently gives the sulfonate 7 by hydrolysis. The action of hydrogen peroxide, with or without boric acid, leads to the sulfinate 4 by S-S bond cleavage. Its oxidation gives sulfonate 7. Finally, reactions of MMPP and m-CPBA afford sulfonate 7 but no intermediates are highlighted with these reagents.

Domaines

Chimie organique

Dates et versions

hal-00167977 , version 1 (23-08-2007)

Identifiants

Citer

Thierry Cassagne, Henri-Jean Cristau, Gérard Delmas, Michel Desgranges, Claude Lion, et al.. Reactions of N,N-diisopropyl-2-aminoethylp-fluorobenzene thiosulfonate with oxidising agents. Comptes rendus de l’Académie des sciences. Série IIc, Chimie, 2001, 4 (4), pp.309-314. ⟨10.1016/S1387-1609(01)01231-2⟩. ⟨hal-00167977⟩
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