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Article Dans Une Revue Microbes and Infection Année : 2002

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response.

Résumé

The molecular bases of Mycobacterium tuberculosis pathogenicity remain unclear. We report here how M. tuberculosis mannosylated lipoarabinomannans contribute to the survival of bacilli in the human reservoir by (i) inhibiting IL-12 production by macrophages and dendritic cells and (ii) modulating M. tuberculosis-induced macrophage apoptosis.
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Dates et versions

hal-00177974 , version 1 (09-10-2007)

Identifiants

  • HAL Id : hal-00177974 , version 1
  • PUBMED : 12106787

Citer

Jérôme Nigou, Martine Gilleron, Mauricio Rojas, Luis F García, Martin Thurnher, et al.. Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response.. Microbes and Infection, 2002, 4 (9), pp.945-53. ⟨hal-00177974⟩
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