Stimulus-dependency in the power-law scaling of the subthreshold activity of V1 cells - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Communication Dans Un Congrès Année : 2008

Stimulus-dependency in the power-law scaling of the subthreshold activity of V1 cells

Résumé

The power spectra of many nonlinear systems can display power-law frequency scaling with a fractional exponent. Such fractal behavior has been reported using various observables of neural activity from spike train statistics [4] to population dynamics [5]. However the origin of such scaling invariance remains controversial [6]. The analysis of the subthreshold membrane activity (Vm) in single neurons can help to dissect out the possible origins of the power-law. In the anesthetized and paralyzed cat, we recorded the intracellular response of V1 neurons to visual stimuli of various spatio-temporal statistics. We observed that, for each cell, the fractal exponent changes in a rather systematic way according to the stimulus. Such a dependency implies that local network dynamics are involved in the genesis of this power-law. We designed a model which derives the fractal exponent modulation from the topology of the functional connectivity. Using Cluster Point Process theory [2], we showed analytically that this effect depends on synchrony within local assemblies and that the emergence of power-law is further determined by the scaling property of network interactions. We led numerical simulations to confirm the power-law change at the Vm level. To check if those variations can be influenced by the cell intrinsic properties, this paradigm has been investigated in vitro using dynamic-clamp injections of generated conductances that reproduce fractal behaviour.
Fichier principal
Vignette du fichier
NEUROCOMP2008_0032.pdf (13.81 Ko) Télécharger le fichier
Origine : Accord explicite pour ce dépôt
Loading...

Dates et versions

hal-00331572 , version 1 (17-10-2008)

Identifiants

  • HAL Id : hal-00331572 , version 1

Citer

Olivier Marre, Sami El Boustani, Sébastien Béhuret, Cyril Monier, Thierry Bal, et al.. Stimulus-dependency in the power-law scaling of the subthreshold activity of V1 cells. Deuxième conférence française de Neurosciences Computationnelles, "Neurocomp08", Oct 2008, Marseille, France. ⟨hal-00331572⟩

Collections

CNRS NEUROCOMP08
113 Consultations
34 Téléchargements

Partager

Gmail Facebook X LinkedIn More