The cis-regulatory sequences required for expression of the Drosophila melanogaster adult cuticle gene ACP65A - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Insect Molecular Biology Année : 2009

The cis-regulatory sequences required for expression of the Drosophila melanogaster adult cuticle gene ACP65A

Résumé

Post-embryonic development in insects requires successive molts. Molts are triggered by ecdysteroids, and the nature of the molt (larval, pupal or adult) is determined by juvenile hormones. The genes encoding cuticle proteins are targets of both classes of hormones, and therefore are interesting models to study hormone action at the molecular level. The Drosophila ACP65A cuticle gene is expressed exclusively during the synthesis of the adult exoskeleton, in epidermal domains synthesising flexible cuticle. We have examined the cis-regulatory sequences of ACP65A using phylogenetic comparisons and functional analysis, and find that only about 180†bp are essential, including an 81†bp intron. The restriction of ACP65A expression appears to depend on a strong repression mechanism

Dates et versions

hal-00450639 , version 1 (26-01-2010)

Identifiants

Citer

Mathieu Lestradet, Edgar Gervasio, Stéphane Fraichard, Stéphane Dupas, Josiane Alabouvette, et al.. The cis-regulatory sequences required for expression of the Drosophila melanogaster adult cuticle gene ACP65A. Insect Molecular Biology, 2009, 18 (4), pp.431-41. ⟨10.1111/j.1365-2583.2009.00893.x⟩. ⟨hal-00450639⟩
26 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More