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Article Dans Une Revue Biochemical Society Transactions Année : 2010

Virtual mitochondrion: towards an integrated model of oxidative phosphorylation complexes and beyond.

Résumé

The modelling of OXPHOS (oxidative phosphorylation) in order to integrate all kinetic and thermodynamic aspects of chemiosmotic theory has a long history. We briefly review this history and show how new ways of modelling are required to integrate a local model of the individual respiratory complexes into a global model of OXPHOS and, beyond that, into a reliable overall model of central metabolism.
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Dates et versions

hal-00526684 , version 1 (15-10-2010)

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Jean-Pierre Mazat, Jonathan Fromentin, Margit Heiske, Christine Nazaret, Stéphane Ransac. Virtual mitochondrion: towards an integrated model of oxidative phosphorylation complexes and beyond.. Biochemical Society Transactions, 2010, 38 (5), pp.1215-9. ⟨10.1042/BST0381215⟩. ⟨hal-00526684⟩
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