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Article Dans Une Revue Chemical Communications Année : 2011

The crystallographic structure of thermoNicotianamine synthase with a synthetic reaction intermediate highlights the sequential processing mechanism

Résumé

We determined th three-dimensional structure of a complex between an archaeal nicotianamine synthase homologue and a chemically synthesised reaction intermediate. This structure suggests that the enzymes cavity allows both an ordered substrate binding and provides energetic coupling of the reaction intermediate formation and translocation

Domaines

Chimie organique
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Dates et versions

hal-00599286 , version 1 (09-06-2011)

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Cyril Dreyfus, Manuel Larrouy, Florine Cavelier, Jean Martinez, David Pignol, et al.. The crystallographic structure of thermoNicotianamine synthase with a synthetic reaction intermediate highlights the sequential processing mechanism. Chemical Communications, 2011, 47, pp.5825-5827. ⟨10.1039/c1cc10565e⟩. ⟨hal-00599286⟩
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