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Article Dans Une Revue Journal of Mammary Gland Biology and Neoplasia Année : 2010

The role of histone modifications and variants in regulating gene expression in breast cancer.

Résumé

The role of epigenetic phenomena in cancer biology is increasingly being recognized. Here we focus on the mechanisms and enzymes involved in regulating histone methylation and acetylation, and the modulation of histone variant expression and deposition. Implications of these epigenetic marks for tumor development, progression and invasiveness are discussed with a particular emphasis on breast cancer progression.

Dates et versions

hal-00611848 , version 1 (27-07-2011)

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Mathieu Dalvai, Kerstin Bystricky. The role of histone modifications and variants in regulating gene expression in breast cancer.. Journal of Mammary Gland Biology and Neoplasia, 2010, 15 (1), pp.19-33. ⟨10.1007/s10911-010-9167-z⟩. ⟨hal-00611848⟩
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