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Article Dans Une Revue Organic & Biomolecular Chemistry Année : 2012

Original β,γ-diamino acid as an inducer of a γ-turn mimic in short peptides.

Résumé

Original αγα tripeptides containing one β,γ-diamino acid have been synthesized and their conformation determined by extensive NMR and molecular dynamic studies. These studies revealed the presence of a C(9) hydrogen bonded turn around the β,γ-diamino acid which was stabilized by bulky side chains of the preceding residue. This turn can be considered as a mimic of the well-known γ-turn.

Domaines

Chimie organique
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Dates et versions

hal-00751282 , version 1 (13-11-2012)

Identifiants

Citer

Sophie Thétiot-Laurent, Francelin Bouillère, Jean-Pierre Baltaze, François Brisset, Debby Feytens, et al.. Original β,γ-diamino acid as an inducer of a γ-turn mimic in short peptides.. Organic & Biomolecular Chemistry, 2012, 10, pp.9660-9663. ⟨10.1039/c2ob26828k⟩. ⟨hal-00751282⟩
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