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Communication Dans Un Congrès Année : 2012

Automated Cancer Marker Characterization in Human Plasma Using SUrface PLASMON Resonance in Array combined with Mass Spectrometry (SUPRA-MS)

Résumé

The combination of Surface Plasmon Resonance technology with Mass Spectrometry becomes a key method for the characterization of targeted proteins in the fields of diagnosis and functional proteomics. We demonstrated in this work the ability of our SPRi-chip to capture targeted protein in biological fluids and in situ analyze by MS and MS/MS modes through automated procedure to go beyond classical immunoassays. Here, we established a proof of concept of SUPRA-MS for the detection, the identification and the characterization of a potential breast cancer marker.

Dates et versions

hal-00771203 , version 1 (08-01-2013)

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Citer

Fabien Remy-Martin, Marven El Ostab, Géraldine Lucchi, Rabah Zeggari, Therese Leblois, et al.. Automated Cancer Marker Characterization in Human Plasma Using SUrface PLASMON Resonance in Array combined with Mass Spectrometry (SUPRA-MS). 2nd International Conference on Bio-Sensing Technology, Oct 2012, Amsterdam, Netherlands. pp.11-19, ⟨10.1016/j.proche.2012.10.125⟩. ⟨hal-00771203⟩
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