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Article Dans Une Revue Organic Letters Année : 2010

New family of peptidomimetics based on the imidazole motif.

Résumé

Starting from amino acid esters, new peptidomimetics based on the imidazole scaffold were prepared. An efficient and rapid sequence consisting of two subsequent one-pot procedures was developed and applied to various aminoacids. As they provide more substitution patterns, these heterocyclic mimics are promising tools for structural and biological studies.

Domaines

Chimie organique
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Dates et versions

hal-00992144 , version 1 (16-05-2014)

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Sylvain Petit, Corinne Fruit, Laurent Bischoff. New family of peptidomimetics based on the imidazole motif.. Organic Letters, 2010, 12 (21), pp.4928-4931. ⟨10.1021/ol102118u⟩. ⟨hal-00992144⟩
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