Original design of fluorescent ligands by fusing Bodipy and melatonin neurohormone - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue ACS Medicinal Chemistry Letters Année : 2014

Original design of fluorescent ligands by fusing Bodipy and melatonin neurohormone

Résumé

An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I–IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.

Domaines

Autre [q-bio.OT]

Dates et versions

hal-01129794 , version 1 (10-03-2015)

Identifiants

Citer

Jérémy Thireau, Justine Marteaux, Philippe Delagrange, François Lefoulon, Laurence Dufourny, et al.. Original design of fluorescent ligands by fusing Bodipy and melatonin neurohormone. ACS Medicinal Chemistry Letters, 2014, 5 (2), pp.158-161. ⟨10.1021/ml4004155⟩. ⟨hal-01129794⟩
66 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More