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Article Dans Une Revue Lab on a Chip Année : 2016

Asymmetric axonal edge guidance: a new paradigm for building oriented neuronal networks

Résumé

We present a novel kind of directional axon guides for brain-on-a-chip applications. Contrarily to previous works, the directionality in our design is created by rerouting axons growing in the unwanted direction back to their original compartment while leaving the other growth direction unaffected. This design yields state-of-the-art levels of directionality without the disadvantages of previously reported technologies.
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Dates et versions

hal-01336980 , version 1 (24-06-2016)

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Renaud Renault, Jean-Baptiste Durand, Jean-Louis Viovy, Catherine Villard. Asymmetric axonal edge guidance: a new paradigm for building oriented neuronal networks. Lab on a Chip, 2016, 16 (12), pp.2188-2191. ⟨10.1039/C6LC00479B⟩. ⟨hal-01336980⟩
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