Dental pain induced by an ambient thermal differential: pathophysiological hypothesis - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Journal of Pain Research Année : 2017

Dental pain induced by an ambient thermal differential: pathophysiological hypothesis

Résumé

Dental pain triggered by temperature differential is a misrecognized condition and a form of dental allodynia. Dental allodynia is characterized by recurrent episodes of diffuse, dull and throbbing tooth pain that develops when returning to an indoor room temperature after being exposed for a long period to cold weather. The pain episode may last up to few hours before subsiding. Effective treatment is to properly shield the pulpal tissue of the offending tooth by increasing the protective layer of the dentin/enamel complex. This review underscores the difference in dentin hypersensitivity and offers a mechanistic hypothesis based on the following processes. Repeated exposure to significant positive temperature gradients (from cold to warm) generates phenotypic changes of dental primary afferents on selected teeth with subsequent development of a “low-grade” neurogenic inflammation. As a result, nociceptive C-fibers become sensitized and responsive to innocuous temperature gradients because the activation threshold of specific TRP ion channels is lowered and central sensitization takes place. Comprehensive overviews that cover dental innervation and sensory modalities, thermodynamics of tooth structure, mechanisms of dental nociception and the thermal pain are also provided.
Fichier principal
Vignette du fichier
Dental pain induced by an ambient thermal differential - Pathophysiological hypothesis.pdf (593.09 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-01690450 , version 1 (23-01-2018)

Identifiants

Citer

Anais Le Fur Bonnabesse, Céline Bodéré, Cyrielle Hélou, Valérie Chevalier, Jean-Paul Goulet. Dental pain induced by an ambient thermal differential: pathophysiological hypothesis. Journal of Pain Research, 2017, 10, pp.2845-2851. ⟨10.2147/JPR.S142539⟩. ⟨hal-01690450⟩
132 Consultations
83 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More