Biodegradation and toxicity of a maize herbicide mixture: mesotrione, nicosulfuron and S-metolachlor - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Journal of Hazardous Materials Année : 2018

Biodegradation and toxicity of a maize herbicide mixture: mesotrione, nicosulfuron and S-metolachlor

Résumé

The prediction of chemical mixture toxicity is a major concern regarding unintentional mixture of pesticides from agricultural lands treated with various such compounds. We focused our work on a mixture of three herbicides commonly applied on maize crops within a fortnight, namely mesotrione (β-triketone), nicosulfuron (sulfonylurea) and S-metolachlor (chloroacetanilide). The metabolic pathways of mesotrione and nicosulfuron were qualitatively and quantitatively determined with a bacterial strain (Bacillus megaterium Mes11). This strain was isolated from an agricultural soil and able to biotransform both these herbicides. Although these pathways were unaffected in the case of binary or ternary herbicide mixtures, kinetics of nicosulfuron disappearance and also of mesotrione and nicosulfuron metabolite formation was strongly modulated. The toxicity of the parent compounds and metabolites was evaluated for individual compounds and mixtures with the standardized Microtox® test. Synergistic interactions were evidenced for all the parent compound mixtures. Synergistic, antagonistic or additive toxicity was obtained depending on the metabolite mixture. Overall, these results emphasize the need to take into account the active ingredient and metabolites all together for the determination of environmental fate and toxicity of pesticide mixtures.
Fichier principal
Vignette du fichier
Carles et al 2018.pdf (462.95 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Licence : CC BY - Paternité

Dates et versions

hal-01785204 , version 1 (08-12-2023)

Identifiants

Citer

Louis Carles, Muriel Joly, Frédérique Bonnemoy, Martin Leremboure, Florence Donnadieu, et al.. Biodegradation and toxicity of a maize herbicide mixture: mesotrione, nicosulfuron and S-metolachlor. Journal of Hazardous Materials, 2018, 354, pp.42 - 53. ⟨10.1016/j.jhazmat.2018.04.045⟩. ⟨hal-01785204⟩
165 Consultations
16 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More