Characterization of a novel composite staphylococcal cassette chromosome mec (SCCmec-SCCcad/ars/cop) in the neonatal sepsis-associated Staphylococcus capitis pulsotype NRCS-A - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Antimicrobial Agents and Chemotherapy Année : 2013

Characterization of a novel composite staphylococcal cassette chromosome mec (SCCmec-SCCcad/ars/cop) in the neonatal sepsis-associated Staphylococcus capitis pulsotype NRCS-A

Résumé

Multiresistant Staphylococcus capitis pulsotype NRCS-A has been reported to be a major pathogen causing nosocomial bacteremia in preterm infants. We report that the NRCS-A strain CR01 harbors a novel 60.9-kb composite staphylococcal cassette chromosome mec (SCCmec) element, composed of an SCCmec with strong homologies to Staphylococcus aureus ST398 SCCmec and of an SCCcad/ars/cop harboring resistance genes for cadmium, arsenic, and copper. Whole-genome-based comparisons of published S. capitis strains suggest that strain CR01 acquired the two elements independently.

Dates et versions

hal-01909019 , version 1 (30-10-2018)

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Patricia Martins Simões, Jean-Philippe Rasigade, H. Lemriss, Marine Butin, Christophe Ginevra, et al.. Characterization of a novel composite staphylococcal cassette chromosome mec (SCCmec-SCCcad/ars/cop) in the neonatal sepsis-associated Staphylococcus capitis pulsotype NRCS-A. Antimicrobial Agents and Chemotherapy, 2013, 57 (12), pp.6354-6357. ⟨10.1128/AAC.01576-13⟩. ⟨hal-01909019⟩
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