Methicillin-susceptible Staphylococcus aureus clonal complex 398: high prevalence and geographical heterogeneity in bone and joint infection and nasal carriage
Résumé
The prevalence of clonal complex (CC) 398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.
Mots clés
Adult
Aged
Arthritis
Infectious
bone and joint infection
Bone Diseases
Carrier State
Clonal complex~398
Female
Humans
Male
Methicillin-Resistant Staphylococcus aureus
methicillin-susceptible Staphylococcus aureus
Middle Aged
molecular epidemiology
nasal carriage
Nose
Prevalence
Retrospective Studies
Staphylococcal Infections
Staphylococcus aureus
virulence factors