Head to tail cyclisation of cell-penetrating peptides: impact on GAG-dependent internalisation and direct translocation
Résumé
A series of cyclic lipidated oligo-Arg cell penetrating peptides were synthesised with varied macrocycle size and lipid chain anchoring site. The study of their cellular uptake revealed different structural requirements to promote efficient glycosaminoglycan-dependent endocytosis and direct translocation.
Domaines
Chimie
Origine : Fichiers produits par l'(les) auteur(s)
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