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Article Dans Une Revue European Journal of Organic Chemistry Année : 2019

A HELIXOL-Derived Bisphosphinite Ligand: Synthesis and Application in Gold-Catalyzed Enynes Cycloisomerization

Corinne Aubert
Etienne Derat
Louis Fensterbank
Cyril Ollivier

Résumé

The synthesis, optical resolution through derivatization, characterization, and utilization of a new helical bis(phosphinite gold) complex derived from HELIXOL are described. By using an efficient cobalt catalyst, neither irradiation nor high catalytic loading was required to access the helicene of interest. The latter was phosphorylated to afford a new chiral ligand that was studied. Especially, treatment with AuCl(SMe2) gives a dinuclear gold complex that was used in cycloisomerization reactions.

Domaines

Chimie
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Dates et versions

hal-02189404 , version 1 (29-08-2019)

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Citer

Caleb Medena, Francesco Calogero, Quentin Lemoine, Corinne Aubert, Etienne Derat, et al.. A HELIXOL-Derived Bisphosphinite Ligand: Synthesis and Application in Gold-Catalyzed Enynes Cycloisomerization. European Journal of Organic Chemistry, 2019, 2019 (11), pp.2129-2137. ⟨10.1002/ejoc.201801722⟩. ⟨hal-02189404⟩
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