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Article Dans Une Revue Materials Horizons Année : 2019

Self-mineralization and assembly of a bis-silylated Phe–Phe pseudodipeptide to a structured bioorganic–inorganic material

Arie van Der Lee

Résumé

Self-mineralization of trialkoxysilyl hybrid peptide yield in a single step a nanostructured hybrid material. A bis-silylated pseudodipeptide inspired from the Phe-Phe dipeptide was used to program the assembly by sol-gel polymerization in heterogeneous conditions, in water at pH 1.5 without any structure-directing agent. A mechanism deciphering the hybrid material assembly was proposed thanks to 1H NMR spectroscopy. First, water-insoluble hybrid building blocks were hydrolysed into their soluble silanol counterparts. Then, these transitional species, thanks to hydrogen bonding and π-π stacking, self-assembled in solution. Last, the proximity of silanol moieties favoured their polycondensation into growing siloxane oligomers, which spontaneously precipitated to produce an ordered hybrid material.

Domaines

Matériaux
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Dates et versions

hal-02372976 , version 1 (20-12-2019)

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Said Jebors, Laurine Valot, Cécile Echalier, Baptiste Legrand, Remi Mikhaleff, et al.. Self-mineralization and assembly of a bis-silylated Phe–Phe pseudodipeptide to a structured bioorganic–inorganic material. Materials Horizons, 2019, 6 (10), pp.2040-2046. ⟨10.1039/c9mh00580c⟩. ⟨hal-02372976⟩
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