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Article Dans Une Revue Nature Genetics Année : 2014

Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle

Songlin Chen
  • Fonction : co premier-auteur
Changwei Shao
  • Fonction : co premier-auteur
Geng Liu
  • Fonction : co premier-auteur
Pei Zhang
  • Fonction : co premier-auteur
  • PersonId : 760867
  • IdRef : 219887357
Yang Liu
  • Fonction : Auteur
Na Wang
Jing Zhang
  • Fonction : Auteur
  • PersonId : 757517
  • IdRef : 164499075
Manfred Schartl

Résumé

Genetic sex determination by W and Z chromosomes has developed independently in different groups of organisms. To better understand the evolution of sex chromosomes and the plasticity of sex-determination mechanisms, we sequenced the whole genomes of a male (ZZ) and a female (ZW) half-smooth tongue sole (Cynoglossus semilaevis). In addition to insights into adaptation to a benthic lifestyle, we find that the sex chromosomes of these fish are derived from the same ancestral vertebrate protochromosome as the avian W and Z chromosomes. Notably, the same gene on the Z chromosome, dmrt1, which is the male-determining gene in birds, showed convergent evolution of features that are compatible with a similar function in tongue sole. Comparison of the relatively young tongue sole sex chromosomes with those of mammals and birds identified events that occurred during the early phase of sex-chromosome evolution. Pertinent to the current debate about heterogametic sex-chromosome decay, we find that massive gene loss occurred in the wake of sex-chromosome 'birth'.
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hal-02637825 , version 1 (28-05-2020)

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Songlin Chen, Guojie Zhang, Changwei Shao, Quanfei Huang, Geng Liu, et al.. Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle. Nature Genetics, 2014, 46 (3), pp.253-262. ⟨10.1038/ng.2890⟩. ⟨hal-02637825⟩
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