Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines. - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Neuroscience bulletin Année : 2019

Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.

Neng-Yuan Hu
  • Fonction : Auteur
Ya-Ting Chen
  • Fonction : Auteur
Qian Wang
Wei Jie
  • Fonction : Auteur
Yi-Si Liu
  • Fonction : Auteur
Qiang-Long You
  • Fonction : Auteur
Ze-Lin Li
  • Fonction : Auteur
Xiao-Wen Li
  • Fonction : Auteur
Jian-Ming Yang
  • Fonction : Auteur
Tian-Ming Gao
  • Fonction : Auteur

Résumé

Astrocytes are the most abundant cell type in the central nervous system (CNS). They provide trophic support for neurons, modulate synaptic transmission and plasticity, and contribute to neuronal dysfunction. Many transgenic mouse lines have been generated to obtain astrocyte-specific expression of inducible Cre recombinase for functional studies; however, the expression patterns of inducible Cre recombinase in these lines have not been systematically characterized. We generated a new astrocyte-specific Aldh1l1-CreER

Dates et versions

hal-02884513 , version 1 (29-06-2020)

Identifiants

Citer

Neng-Yuan Hu, Ya-Ting Chen, Qian Wang, Wei Jie, Yi-Si Liu, et al.. Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.. Neuroscience bulletin, 2019, 36, pp.530-544. ⟨10.1007/s12264-019-00451-z⟩. ⟨hal-02884513⟩

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