MiBiOmics: An interactive web application for multi-omics data exploration and integration - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Pré-Publication, Document De Travail Année : 2020

MiBiOmics: An interactive web application for multi-omics data exploration and integration

Johanna Zoppi
Jean-François Guillaume
  • Fonction : Auteur
Michel Neunlist

Résumé

Background: Multi-omics experimental approaches are becoming common practice in biological and medical sciences underlying the need to design new integrative techniques and applications to enable the holistic characterization of biological systems. The integrative analysis of heterogeneous datasets generally allows us to acquire additional insights and generate novel hypotheses about a given biological system. However, it can often become challenging given the large size of omics datasets and the diversity of existing techniques. Moreover, visualization tools for interpretation are usually non-accessible to biologists without programming skills. Results: Here, we present MiBiOmics, a web-based and standalone application that facilitates multi-omics data visualization, exploration, integration, and analysis by providing easy access to dedicated and interactive protocols. It implements advanced ordination techniques and the inference of omics-based (multi-layer) networks to mine complex biological systems, and identify robust biomarkers linked to specific contextual parameters or biological states. Conclusions: Through an intuitive and interactive interface, MiBiOmics provides easy-access to ordination techniques and to a network-based approach for integrative multi-omics analyses.
Fichier principal
Vignette du fichier
2020.04.24.031773v1.full.pdf (6.3 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-02946891 , version 1 (05-01-2021)

Identifiants

Citer

Johanna Zoppi, Jean-François Guillaume, Michel Neunlist, Samuel Chaffron. MiBiOmics: An interactive web application for multi-omics data exploration and integration. 2020. ⟨hal-02946891⟩
79 Consultations
41 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More