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Journal Articles Biophysical Journal Year : 2020

Amoeboid Swimming Is Propelled by Molecular Paddling in Lymphocytes

Laurene Aoun
  • Function : relator_co_first_author
Alexander Farutin
Nicolas Garcia-Seyda
  • Function : relator_co_first_author
Paulin Nègre
  • Function : relator_co_first_author
Claire Hivroz

Abstract

Mammalian cells developed two main migration modes. The slow mesenchymatous mode, like crawling of fibroblasts, relies on maturation of adhesion complexes and actin fibre traction, while the fast amoeboid mode, observed exclusively for leukocytes and cancer cells, is characterized by weak adhesion, highly dynamic cell shapes, and ubiquitous motility on 2D and in 3D solid matrix. In both
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Dates and versions

hal-03006653 , version 1 (17-12-2020)

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Laurene Aoun, Alexander Farutin, Nicolas Garcia-Seyda, Paulin Nègre, Mohd Suhail Rizvi, et al.. Amoeboid Swimming Is Propelled by Molecular Paddling in Lymphocytes. Biophysical Journal, 2020, 119 (6), pp.1157-1177. ⟨10.1016/j.bpj.2020.07.033⟩. ⟨hal-03006653⟩
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