%0 Journal Article %T Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses %+ University of Fribourg %+ Universitat Pompeu Fabra [Barcelona] (UPF) %+ University of Freiburg [Freiburg] %+ University of Edinburgh %+ University of St Andrews [Scotland] %+ University of Basel (Unibas) %+ Instituto de Biologia Molecular e Celular - institute for molecular and cell biology [Porto, Portugal] (IBMC) %+ Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) %+ Fondazione Edmund Mach [San Michele all'Adige] %+ University of Jyväskylä (JYU) %+ National University of Kyiv-Mohyla Academy (UKMA) %+ Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia] %+ Aarhus University [Aarhus] %+ Universitat de Barcelona (UB) %+ Eléments transposables, évolution, populations %+ Département génétique, interactions et évolution des génomes [LBBE] (GINSENG) %+ Equipe de recherche européenne en algorithmique et biologie formelle et expérimentale (ERABLE) %+ Evolution, génomes, comportement et écologie (EGCE) %+ Lund University [Lund] %+ Génétique et évolution des interactions hôtes-parasites %+ Department of Animal and Plant Sciences [Sheffield] %+ Georg-August-University = Georg-August-Universität Göttingen %+ Ludwig-Maximilians-Universität München (LMU) %+ Instituto Gulbenkian de Ciência [Oeiras] (IGC) %+ University of Virginia %+ Universitat Autònoma de Barcelona (UAB) %+ Hacettepe University = Hacettepe Üniversitesi %+ School of Life Sciences [Lausanne] %+ Wageningen University and Research [Wageningen] (WUR) %+ University of Haifa [Haifa] %+ University of Pennsylvania %+ University of Liverpool %+ Université de Lausanne = University of Lausanne (UNIL) %A Kapun, Martin %A Barrón, Maite, G %A Staubach, Fabian %A Obbard, Darren, J %A W. Wiberg, R Axel %A Vieira, Jorge %A Goubert, Clément %A Rota-Stabelli, Omar %A Kankare, Maaria %A Bogaerts-Márquez, María %A Haudry, Annabelle, A. %A Waidele, Lena %A Kozeretska, Iryna %A Pasyukov, Elena G %A Loeschcke, Volker %A Pascual, Marta %A Vieira, Cristina P %A Serga, Svitlana %A Montchamp-Moreau, Catherine %A Abbott, Jessica %A Gibert, Patricia %A Porcelli, Damiano %A Posnien, Nico %A Sánchez-Gracia, Alejandro %A Grath, Sonja %A Sucena, Élio %A Bergland, Alan, O %A Garcia Guerreiro, Maria Pilar %A Sebnem Onder, Banu %A Argyridou, Eliza %A Guio, Lain %A Schou, Fristrup %A Deplancke, Bart %A Vieira, Cristina %A Ritchie, Michael, G %A Zwaan, Bas, J %A Tauber, Eran %A Orengo, Dorcas, J %A Puerma, Eva %A Aguadé, Montserrat %A Schmidt, Paul, S %A Parsch, John %A Betancourt, Andrea, J %A Flatt, Thomas %A González, Josefa %< avec comité de lecture %@ 0737-4038 %J Molecular Biology and Evolution %I Oxford University Press (OUP) %V 37 %N 9 %P 2661-2678 %8 2020-09 %D 2020 %R 10.1093/molbev/msaa120 %Z Environmental Sciences/Biodiversity and Ecology %Z Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] %Z Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE] %Z Life Sciences [q-bio]/Ecology, environment/SymbiosisJournal articles %X Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples. %G English %2 https://cnrs.hal.science/hal-03014405/document %2 https://cnrs.hal.science/hal-03014405/file/Kapun_et_al_Revision_R02_AA.pdf %L hal-03014405 %U https://cnrs.hal.science/hal-03014405 %~ IRD %~ SDE %~ CNRS %~ INRIA %~ UNIV-LYON1 %~ INRIA-RHA %~ INRIA_TEST %~ GIP-BE %~ TESTALAIN1 %~ BIOENVIS %~ INRIA2 %~ INRIA-EPFL %~ UNIV-PARIS-SACLAY %~ INRIA-RENGRE %~ LBBE %~ UDL %~ UNIV-LYON %~ UNIVERSITE-PARIS-SACLAY %~ EGCE %~ GS-BIOSPHERA %~ GS-LIFE-SCIENCES-HEALTH %~ INRIAARTDOI %~ INRIA-ISRAEL %~ INRIA-ETATSUNIS %~ INRIA-ROYAUMEUNI