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Article Dans Une Revue Annual Review of Genetics Année : 2014

Population Genomics of Transposable Elements in Drosophila

Résumé

Studies of the population dynamics of transposable elements (TEs) inDrosophila melanogasterindicate that consistent forces are affecting TEs inde-pendently of their modes of transposition and regulation. New sequencingtechnologies enable biologists to sample genomes at an unprecedented scalein order to quantify genome-wide polymorphism for annotated and novelTE insertions. In this review, we first present new insights gleaned fromhigh-throughput data for population genomics studies ofD. melanogaster.We then consider the latest population genomics models for TE evolutionand present examples of functional evidence revealed by genome-wide stud-ies of TE population dynamics inD. melanogaster. Although most of the TEinsertions are deleterious or neutral, some TE insertions increase the fitnessof the individual that carries them and play a role in genome adaptation
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Dates et versions

hal-03041181 , version 1 (04-12-2020)

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Maite Barrón, Anna-Sophie Fiston-Lavier, Dmitri Petrov, Josefa González. Population Genomics of Transposable Elements in Drosophila. Annual Review of Genetics, 2014, 48 (1), pp.561-581. ⟨10.1146/annurev-genet-120213-092359⟩. ⟨hal-03041181⟩
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