%0 Journal Article %T Exploring protein space: From hydrolase to ligase by substitution %+ Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) %A Hecht, Nir %A Monteil, Caroline %A Perriere, Guy %A Vishkautzan, Marina %A Gur, Eyal %< avec comité de lecture %@ 0737-4038 %J Molecular Biology and Evolution %I Oxford University Press (OUP) %8 2020-09-01 %D 2020 %R 10.1093/molbev/msaa215 %K Dop %K PafA %K Pup %K structure-function %K molecular evolution %Z Life Sciences [q-bio]/Quantitative Methods [q-bio.QM] %Z Life Sciences [q-bio] %Z Chemical Sciences/CristallographyJournal articles %G English %2 https://cnrs.hal.science/hal-03046442/document %2 https://cnrs.hal.science/hal-03046442/file/msaa215.pdf %L hal-03046442 %U https://cnrs.hal.science/hal-03046442 %~ CNRS %~ INRIA %~ UNIV-LYON1 %~ BIOENVIS %~ INRIA-AUT %~ LBBE %~ UDL %~ UNIV-LYON