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Article Dans Une Revue PLoS ONE Année : 2014

Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients

Résumé

Epithelial-Mesenchymal Transition (EMT) features appear to be key events in development and progression of breast cancer. Epigenetic modifications contribute to the establishment and maintenance of cancer subclasses, as well as to the EMT process. Whether histone variants contribute to these transformations is not known. We investigated the relative expression levels of histone macroH2A1 splice variants and correlated it with breast cancer status/prognosis/types.
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hal-03107782 , version 1 (12-01-2021)

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Anne-Claire Lavigne, Magali Castells, Jérôme Mermet, Silvia Kocanova, Mathieu Dalvai, et al.. Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients. PLoS ONE, 2014, 9 (6), pp.e98930. ⟨10.1371/journal.pone.0098930⟩. ⟨hal-03107782⟩
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