The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1 - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Gastroenterology Année : 2009

The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1

Résumé

Symplekin is a ubiquitously expressed protein involved in RNA polyadenylation and transcriptional regulation that localizes at tight junctions in epithelial cells. The association between symplekin and the Y-box transcription factor ZONAB activates proliferation in intestinal and kidney cells. We analyzed symplekin expression in human colonic crypts and investigated its function in differentiation.
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hal-03108516 , version 1 (13-01-2021)

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Michael Buchert, Charbel Darido, Ebba Lagerqvist, Anna Sedello, Chantal Cazevieille, et al.. The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1. Gastroenterology, 2009, 137 (1), pp.156-164.e3. ⟨10.1053/j.gastro.2009.03.037⟩. ⟨hal-03108516⟩
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