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Communication Dans Un Congrès Année : 2019

A comparison of direct reconstruction algorithms in proton CT

Résumé

Several analytic algorithms have been proposed to incorporate the non-linear path of protons in the reconstruction of a proton CT (pCT) image. This paper presents a comparison between four direct algorithms used in pCT, in terms of spatial resolution and relative stopping power (RSP) accuracy. We have simulated a pCT set up which registers protons individually using Gate, a Monte Carlo simulation tool, with a 200 MeV proton source and two position, direction and energy detectors upstream and downstream from the object. A Catphan 528 phantom and a spiral phantom were imaged to take into account the spatial dependency of the spatial resolution. Each proton's trajectory was estimated using a most likely path (MLP) formalism. The spatial resolution was evaluated using the frequency corresponding to an MTF value of 10%, and the RSP accuracy as the mean value in a homogeneous region. Our results show that methods performing the backprojection before the filtering offer a better spatial resolution (up to +36%) since each proton is directly binned in the image grid according to its MLP. However, this improvement is minor (+2%) at the center of the object, where the intrinsic uncertainty on the MLP estimate is dominant. Regarding the RSP accuracy, all algorithms but one show equivalent results.
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Dates et versions

hal-03128314 , version 1 (02-02-2021)

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  • HAL Id : hal-03128314 , version 1

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Feriel Khellaf, Nils Krah, Jean Michel Létang, Simon Rit. A comparison of direct reconstruction algorithms in proton CT. 2nd Ion Imaging Workshop 2019, Jun 2019, Manchester, United Kingdom. ⟨hal-03128314⟩
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