%0 Journal Article %T Analysis of the evolution of the detection limits of electrochemical nucleic acid biosensors II %+ Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS - UM 4 (UMR 8258 / U1022)) %A Huon Ho, Thu %A Guillon, Francois-Xavier %A Bigey, Pascal %A Bedioui, Fethi %A Lazerges, Mathieu %< avec comité de lecture %@ 1618-2642 %J Analytical and Bioanalytical Chemistry %I Springer Verlag %V 409 %N 18 %P 4335-4352 %8 2017 %D 2017 %R 10.1007/s00216-017-0377-8 %K DNA HYBRIDIZATION DETECTION %K HEPATITIS-B-VIRUS %K WALLED CARBON NANOTUBES %K SEQUENCE-SPECIFIC DNA %K LABEL-FREE DETECTION %K FREE VOLTAMMETRIC DETECTION %K POLYMERASE-CHAIN-REACTION %K FIELD-EFFECT TRANSISTOR %K RANGE ELECTRON-TRANSFER %K METHYLENE-BLUE %Z Chemical Sciences/Analytical chemistry %Z Life Sciences [q-bio]/BiotechnologyJournal articles %X This critical review of electrochemical biosensors allowing direct detection of nucleic acid targets reports on different transduction pathways and their latest breakthroughs. A classification of the various strategies based on the nature of the electrochemical transduction is established to emphasize the efficiency of each of them. It provides an overall picture of the detection limit of the various approaches developed during the last two decades. %G English %L hal-03292740 %U https://cnrs.hal.science/hal-03292740 %~ UNIV-PARIS5 %~ ENSCP %~ CNRS %~ ENSC-PARIS %~ PARISTECH %~ INC-CNRS %~ PSL %~ USPC %~ UNIV-PARIS %~ UP-SANTE %~ TEST-HALCNRS %~ ENSCP-PSL %~ UTCBS %~ TEST2-HALCNRS