%0 Journal Article %T Health-state utility estimates for health technology assessment: a review of the manufacturers’ submissions to the French National Authority for Health %+ Haute Autorité de Santé [Saint-Denis La Plaine] (HAS) %+ CERMES3 - Centre de recherche Médecine, sciences, santé, santé mentale, société (CERMES3 - UMR 8211 / U988 / UM 7) %A Hamers, Ff %A Ghabri, S %A Le Galès, Catherine %< avec comité de lecture %@ 1473-7167 %J Expert Review of Pharmacoeconomics and Outcomes Research %I Expert Reviews %V 17 %N 5 %P 489-494 %8 2017 %D 2017 %R 10.1080/14737167.2017.1289088 %Z Humanities and Social SciencesJournal articles %X Background: Our aim was to review the selection and methods used for deriving health state utility (HSU) estimates included in the cost-utility analyses (CUA) submitted by manufacturers to the National Authority for Health (HAS) during the first 2years after the introduction of the economic evaluation for price setting in France.Methods: We reviewed all manufacturers' submissions that included a CUA and were assessed by HAS by the end of October 2015 (N=34). We reviewed the identification, selection, and methods used to estimate HSU and compared them with those recommended by HAS.Results: A literature review to identify HSU was reported in only 13 (38%) submissions. The instruments for describing HSU were a preference-based generic instrument in 20 (59%) submissions; vignettes in five (15%); a condition-specific instrument in three (9%); and a combination of instruments in six (18%). The valuation perspective was the general population in 26 (76%) submissions; in only nine (26%) submissions, the valuation set was derived from the French general population.Conclusions: We identified numerous concerns in the selection, valuation and use of HSU, as well as a frequent lack of clarity in the methods used. Most submissions (79%) included HSU that did not meet HAS recommendations. %G English %L hal-03479968 %U https://hal-cnrs.archives-ouvertes.fr/hal-03479968 %~ SHS %~ UNIV-PARIS5 %~ CNRS %~ EHESS %~ CERMES3 %~ USPC %~ UNIV-PARIS %~ UP-SOCIETES-HUMANITES %~ TEST-HALCNRS