MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Microorganisms Année : 2021

MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage

Marie-Gladys Robert
  • Fonction : Auteur
Aurélie Hennebique
  • Fonction : Auteur
Tahinamandranto Rasamoelina
  • Fonction : Auteur
Yvan Caspar
  • Fonction : Auteur
Léa Pondérand
  • Fonction : Auteur
Marie Bidart
  • Fonction : Auteur
Harmonie Durand
  • Fonction : Auteur
Marvin Jacquet
Cécile Garnaud
  • Fonction : Auteur
Danièle Maubon

Résumé

The implementation of MALDI-TOF MS in medical microbiology laboratories has revolutionized practices and significantly reduced turnaround times of identification processes. However, although bacteriology quickly benefited from the contributions of this technique, adjustments were necessary to accommodate the specific characteristics of fungi. MALDI-TOF MS is now an indispensable tool in clinical mycology laboratories, both for the identification of yeasts and filamentous fungi, and other innovative uses are gradually emerging. Based on the practical experience of our medical mycology laboratory, this review will present the current uses of MALDI-TOF MS and the adaptations we implemented, to allow their practical execution in a daily routine. We will also introduce some less mainstream applications, like those for fungemia, or even still under development, as is the case for the determination of sensitivity to antifungal agents or typing methods.

Domaines

Mycologie

Dates et versions

hal-03703127 , version 1 (23-06-2022)

Identifiants

Citer

Marie-Gladys Robert, Muriel Cornet, Aurélie Hennebique, Tahinamandranto Rasamoelina, Yvan Caspar, et al.. MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage. Microorganisms, 2021, 9 (6), pp.1283. ⟨10.3390/microorganisms9061283⟩. ⟨hal-03703127⟩
394 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More