The Hazards of Regeneration: From Morgan’s Legacy to Evo-Devo - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Chapitre D'ouvrage Année : 2022

The Hazards of Regeneration: From Morgan’s Legacy to Evo-Devo

Résumé

Abstract In his prominent book Regeneration (1901), T.H. Morgan’s collected and synthesized theoretical and experimental findings from a diverse array of regenerating animals and plants. Through his endeavor, he introduced a new way to study regeneration and its evolution, setting a conceptual framework that still guides today’s research and that embraces the contemporary evolutionary and developmental approaches. In the first part of the chapter, we summarize Morgan’s major tenets and use it as a narrative thread to advocate interpreting regenerative biology through the theoretical tools provided by evolution and developmental biology, but also to highlight potential caveats resulting from the rapid proliferation of comparative studies and from the expansion of experimental laboratory models. In the second part, we review some experimental evo-devo approaches, highlighting their power and some of their interpretative dangers. Finally, in order to further understand the evolution of regenerative abilities, we portray an adaptive perspective on the evolution of regeneration and suggest a framework for investigating the adaptive nature of regeneration.
Fichier principal
Vignette du fichier
Sinigaglia_Alie_Tiozzo_MIMB_second_revision.pdf (782.99 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03815577 , version 1 (24-11-2022)

Identifiants

Citer

Chiara Sinigaglia, Alexandre Alié, Stefano Tiozzo. The Hazards of Regeneration: From Morgan’s Legacy to Evo-Devo. Whole-Body Regeneration, 2450, Springer US, pp.3-25, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2172-1_1⟩. ⟨hal-03815577⟩
34 Consultations
39 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More