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Article Dans Une Revue Nanoscale Année : 2022

Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level

Résumé

Osteoarthritis induces a combination of chemical, structural and nanomechanical changes to collagen fibrils and aggrecan aggregates, the main building blocks of cartilage ECM, that may be mimicked by specific enzymatic reactions.
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Dates et versions

hal-03986333 , version 1 (13-02-2023)

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Ilhem Lilia Jaabar, Pauline Cornette, Antoine Miche, Kristell Wanherdrick, Vincent Dupres, et al.. Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level. Nanoscale, 2022, 14 (24), pp.8691-8708. ⟨10.1039/d2nr00474g⟩. ⟨hal-03986333⟩
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