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Article Dans Une Revue Current Opinion in Immunology Année : 2022

Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease

Résumé

The nervous system and immune system communicate throughout the body and in the central nervous system (CNS). The field of neuroimmunology has enjoyed a recent renaissance. This volume of Current Opinion in Immunology highlights current studies and expert opinions illuminating neuro-immune interactions in health and disease. In peripheral organs and tissues, neurons bidirectionally crosstalk with innate and adaptive immune cells to regulate host defense, allergies, wound healing, and barrier immunity. We also discuss how innate and adaptive immune cell populations change dynamically in brain, spinal cord, and brain-border regions with development, aging, and disease. Immune cells play integral roles in CNS homeostasis and host defense, and their dysregulation very likely underlie autoimmune diseases and neurodegeneration. The gut microbiome and enteric nervous system (ENS) signal to neurons and immune cells to impact both peripheral and CNS inflammation.
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Dates et versions

hal-04009854 , version 1 (01-03-2023)

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Isaac Chiu, Roland Liblau. Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease. Current Opinion in Immunology, 2022, 77, pp.102232. ⟨10.1016/j.coi.2022.102232⟩. ⟨hal-04009854⟩
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