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Article Dans Une Revue Angewandte Chemie Année : 2022

Autonomous Chiral Microswimmers with Self‐mixing Capabilities for Highly Efficient Enantioselective Synthesis

Résumé

The development of chiral catalysts plays a very important role in various areas of chemical science. Heterogeneous catalysts have the general advantage of allowing a more straightforward separation from the products. One specific case of heterogeneous catalysis is electrocatalysis, being potentially a green chemistry approach. However, a typical drawback is that the redox conversion of molecules occurs only at the electrode/electrolyte interface, and not in the bulk of the electrolyte. The second limitation is that the electrodes have to be physically connected to a power supply to induce the desired reactions. To circumvent these problems, we propose here a complementary approach by replacing macroscopic electrodes with an ensemble of self-propelled redox active microswimmers. They move autonomously in solution while transforming simultaneously a prochiral starting compound into a specific enantiomer with a very high enantiomeric excess, accompanied by a significantly increased production rate of the favorite enantiomer.

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Autre
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Dates et versions

hal-04050612 , version 1 (29-03-2023)

Identifiants

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Serena Arnaboldi, Gerardo Salinas, Giorgia Bonetti, Patrick Garrigue, Roberto Cirilli, et al.. Autonomous Chiral Microswimmers with Self‐mixing Capabilities for Highly Efficient Enantioselective Synthesis. Angewandte Chemie, 2022, 134 (40), pp.e202209098. ⟨10.1002/ange.202209098⟩. ⟨hal-04050612⟩
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