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The stress response factor daf-16 /FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease
Francesca Farina
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Emmanuel Lambert
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Lucie Commeau
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François-Xavier Lejeune
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Nathalie Roudier
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Journal articles
hal-01545500v1
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AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease
Rafael P. Vazquez-Manrique
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Francesca Farina
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Karine Cambon
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Maria Dolores Sequedo
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Alex J. Parker
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Journal articles
hal-01545502v1
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Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD
Andrea Vergallo
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Marion Houot
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Enrica Cavedo
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Pablo Lemercier
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Eugeen Vanmechelen
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Journal articles
hal-03489074v1
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β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification
Harald Hampel
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Simone Lista
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Eugeen Vanmechelen
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Henrik Zetterberg
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Filippo Sean Giorgi
et al.
Journal articles
hal-03769540v1
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Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases
Lucile Mégret
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Cloé Mendoza
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Maialen Arrieta Lobo
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Emmanuel Brouillet
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Thi-Thanh-Yen Nguyen
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Journal articles
hal-03869363v1
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Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures
Nicolas Merienne
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Cécile Meunier
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Anne Schneider
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Jonathan Seguin
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Satish Nair
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Journal articles
hal-02087719v1
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Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity
J. Alex Parker
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Rafael P. Vazquez-Manrique
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Cendrine Tourette
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Francesca Farina
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Nicolas Offner
et al.
Journal articles
hal-01545520v1
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Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
Michel Thiebaut de Schotten
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Hovagim Bakardjian
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Habib Benali
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Hugo Bertin
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Joel Bonheur
et al.
Journal articles
hal-02368904v1
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Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease
Andrea Vergallo
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Lucile Mégret
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Simone Lista
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Enrica Cavedo
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Henrik Zetterberg
et al.
Journal articles
hal-03484725v1
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Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice
M. Achour
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S. Le Gras
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C. Keime
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F. Parmentier
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F. Lejeune
et al.
Journal articles
hal-02106606v1
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CAG/CTG and CGG/GCC repeats in human brain reference cDNAs: Outcome in searching for new dynamic mutations
Véronique Albanèse
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Sébastien Holbert
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Claudine Saada
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Sebastian Meier-Ewert
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Anne Sophie Lebre
et al.
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istex
hal-02696172v1
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Biosensing Extracellular Vesicle Subpopulations in Neurodegenerative Disease Conditions
Yacine Mazouzi
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Fadoua Sallem
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Francesca Farina
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Alexis Loiseau
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Natayme Rocha Tartaglia
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hal-03791750v1
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Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin
Lucile Mégret
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Barbara Gris
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Satish Sasidharan Nair
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Jasmin Cevost
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Mary Wertz
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Journal articles
hal-03151218v1
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Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology1
Harald Hampel
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Nicola Toschi
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Claudio Babiloni
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Filippo Baldacci
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Keith Black
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hal-03769699v1
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Effect of Alzheimer's disease risk and protective factors on cognitive trajectories in subjective memory complainers: An INSIGHT‐preAD study
Stefan Teipel
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Enrica Cavedo
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Simone Lista
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Marie‐odile Habert
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Marie‐claude Potier
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hal-03769199v1
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C-elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress
Ilija Melentijevic
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Marton L. Toth
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Meghan L. Arnold
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Ryan J. Guasp
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Girish Harinath
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Journal articles
hal-01545495v1
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NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
Mahmoud A. Pouladi
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Elsa Brillaud
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Yuanyun Xie
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Paola Conforti
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Rona K. Graham
et al.
Journal articles
hal-01545519v1
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Thery
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Kenneth Witwer
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Elena Aikawa
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Maria Jose Alcaraz
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Johnathon Anderson
et al.
Journal articles
hal-02323217v1
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Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington’s disease mice
Lucile Mégret
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Satish Sasidharan Nair
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Julia Dancourt
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Jeff Aaronson
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Jim Rosinski
et al.
Journal articles
inserm-02512089v1
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Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway
Lorene Zerah
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Judith Cohen-Bittan
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Mathieu Raux
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Anthony Meziere
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Cendrine Tourette
et al.
Journal articles
hal-03970430v1
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Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Annemieke T van Der Goot
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Wentao Zhu
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Rafael P Vázquez-Manrique
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Renée I Seinstra
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Katja Dettmer
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Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (37), pp.14912-7. ⟨10.1073/pnas.1203083109⟩
Journal articles
hal-01183088v1
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Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons
Courtney Scerbak
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Elena M. Vayndorf
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J. Alex Parker
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Christian Neri
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Monica Driscoll
et al.
Journal articles
hal-01545512v1
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FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16 INK4a increase
Jessica Voisin
,
Francesca Farina
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Swati Naphade
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Morgane Fontaine
,
Kizito-Tshitoko Tshilenge
et al.
Journal articles
hal-03020775v1
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Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway
Lorene Zerah
,
Judith Cohen-Bittan
,
Mathieu Raux
,
Anthony Meziere
,
Cendrine Tourette
et al.
Journal articles
hal-01414826v1
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The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity
Cendrine Tourette
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Francesca Farina
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Rafael P. Vasquez-Manrique
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Anne-Marie Orfila
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Jessica Voisin
et al.
Journal articles
hal-01076146v1
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Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease
Harald Hampel
,
Simone Lista
,
Christian Neri
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Andrea Vergallo
Journal articles
hal-03488187v1
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Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence
Frederic Parmentier
,
Francois-Xavier Lejeune
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Christian Neri
Journal articles
hal-01545516v1
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Cdc42-interacting protein 4 binds to huntingtin: Neuropathologic and biological evidence for a role in Huntington's disease
Sébastien Holbert
,
Alpaslan Dedeoglu
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Sandrine Humbert
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Frédéric Saudlou
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Robert J. Ferrante
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Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (5), pp.2712 - 2717. ⟨10.1073/pnas.0437967100⟩
Journal articles
hal-02682845v1
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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis
Elena M. Vayndorf
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Courtney Scerbak
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Skyler Hunter
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Jason R. Neuswanger
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Marton Toth
et al.
Journal articles
hal-01545501v1
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Role and therapeutic potential of the pro-longevity factor FOXO and its regulators in neurodegenerative disease
Christian Neri
Journal articles
hal-01545518v1
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