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authFullName_s : David Gentien
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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

Elodie Montaudon , Joanna Nikitorowicz-Buniak , Laura Sourd , Ludivine Morisset , Rania El Botty et al.
Nature Communications, 2020, 11, ⟨10.1038/s41467-020-17697-1⟩
Journal articles hal-02933439v1

PRMT1 Regulates EGFR and Wnt Signaling Pathways and Is a Promising Target for Combinatorial Treatment of Breast Cancer

Samyuktha Suresh , Solène Huard , Amélie Brisson , Fariba Némati , Rayan Dakroub et al.
Cancers, 2022, 14 (2), pp.306. ⟨10.3390/cancers14020306⟩
Journal articles hal-03870159v1
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LRP8 is overexpressed in estrogen-negative breast cancers and a potential target for these tumors

Virginie Maire , Faisal Mahmood , Guillem Rigaill , Mengliang Ye , Amélie Brisson et al.
Cancer Medicine, 2019, 8 (1), pp.325-336. ⟨10.1002/cam4.1923⟩
Journal articles hal-02624466v1
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The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

Cristovao Moreira Sousa , John Russel Mcguire , Morgane Sonia Thion , David Gentien , Pierre de La Grange et al.
EMBO Molecular Medicine, 2013, 5 (2), pp.309-325. ⟨10.1002/emmm.201201546⟩
Journal articles hal-01549113v1

G Protein–coupled Receptors in Radioiodine-refractory Thyroid Cancer in the Era of Precision Medicine

Mathilde Munier , Valentine Suteau , Valérie Seegers , Rym Ben Boubaker , Cécile Reyes et al.
Journal of Clinical Endocrinology and Metabolism, 2021, 106 (8), pp.2221-2232. ⟨10.1210/clinem/dgab343⟩
Journal articles hal-03557034v1

Epigenomic mapping identifies a super-enhancer repertoire that regulates cell identity in bladder cancers through distinct transcription factor networks

Hélène Neyret-Kahn , Jacqueline Fontugne , Xiang Yu Meng , Clarice Groeneveld , Luc Cabel et al.
2022
Preprints, Working Papers, ... hal-03854062v1
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Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells

Sylvie Maubant , Bruno Tesson , Virginie Maire , Mengliang Ye , Guillem Rigaill et al.
PLoS ONE, 2015, 10 (4), 26 p. ⟨10.1371/journal.pone.0122333⟩
Journal articles hal-02639667v1

The Wnt3a targetome in triple-negative breast cancer cell lines

Sylvie Maubant , Bruno Tesson , Virginie Maire , Mengliang Ye , Guillem Rigaill et al.
106. Annual Meeting of the American-Association-for-Cancer-Research (AACR), American Association for Cancer Research (AACR). USA., Apr 2015, Philadelphie, United States. 1 p., ⟨10.1158/1538-7445.AM2015-41⟩
Conference papers hal-02739832v1

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions

Houda Benhelli-Mokrani , Zeyni Mansuroglu , Alban Chauderlier , Benoit Albaud , David Gentien et al.
Nucleic Acids Research, 2018, ⟨10.1093/nar/gky929⟩
Journal articles hal-02404215v1
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A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Jing Liu , Daniela Ottaviani , Meriem Sefta , Céline Desbrousses , Elodie Chapeaublanc et al.
Nature Communications, 2021, 12 (1), pp.1-20. ⟨10.1038/s41467-021-25792-0⟩
Journal articles hal-03374490v1

Prospective, multicenter French study evaluating the clinical impact of the Breast Cancer Intrinsic Subtype-Prosigna® Test in the management of early-stage breast cancers

Delphine Hequet , Céline Callens , David Gentien , Benoit Albaud , Marie-Ange Mouret-Reynier et al.
PLoS ONE, 2017, 12 (10), pp.e0185753. ⟨10.1371/journal.pone.0185753⟩
Journal articles hal-01675231v1

Immune Profiling of Combined Hepatocellular- Cholangiocarcinoma Reveals Distinct Subtypes and Activation of Gene Signatures Predictive of Response to Immunotherapy

Cong Trung Nguyen , Stefano Caruso , Pascale Maille , Aurélie Beaufrère , Jérémy Augustin et al.
Clinical Cancer Research, 2022, 28 (3), pp.540-551. ⟨10.1158/1078-0432.CCR-21-1219⟩
Journal articles hal-03599275v1

Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts

Paul Cottu , Ivan Bièche , Franck Assayag , Rania El Botty , Sophie Chateau-Joubert et al.
Clinical Cancer Research, 2014, 20 (16), pp.4314 - 4325. ⟨10.1158/1078-0432.CCR-13-3230⟩
Journal articles hal-02636087v1

Reference-free transcriptome exploration reveals novel RNAs for prostate cancer diagnosis

Marina Pinskaya , Zohra Saci , Mélina Gallopin , Marc Gabriel , Ha Tn Nguyen et al.
Life Science Alliance, 2019, 2 (6), pp.e201900449. ⟨10.26508/lsa.201900449⟩
Journal articles hal-02387126v1

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2

Laura Duciel , Océane Anezo , Kalpana Mandal , Cécile Laurent , Nathalie Planque et al.
Scientific Reports, 2019, 9 (1), pp.2990. ⟨10.1038/s41598-019-39643-y⟩
Journal articles hal-02332471v1

Reliable subtype classification of diffuse large B-cell lymphoma samples from GELA LNH2003 trials using the Lymph2Cx gene expression assay

Jean-Philippe Jais , Thierry Jo Molina , Philippe Ruminy , David Gentien , Cecile Reyes et al.
Haematologica, 2017, 102 (10), pp.e404-e406. ⟨10.3324/haematol.2017.166827⟩
Journal articles hal-02329580v1

Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer

Nanor Sirab , Damien Drubay , Pascale Maillé , Tatiana G. Popova , Carine Ngo et al.
Journal of Pathology, 2022, 256 (1), pp.108-118. ⟨10.1002/path.5813⟩
Journal articles hal-03524517v1
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Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

Barbara Piasecka , Darragh Duffy , Alejandra Urrutia , Hélène Quach , Etienne Patin et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (3), pp.E488 - E497. ⟨10.1073/pnas.1714765115⟩
Journal articles pasteur-01721850v1

TIPIN depletion leads to apoptosis in breast cancer cells

Céline Baldeyron , Amélie Brisson , Bruno Tesson , Fariba Nemati , Stéphane Koundrioukoff et al.
Molecular Oncology, 2015, 9 (8), pp.1580-1598. ⟨10.1016/j.molonc.2015.04.010⟩
Journal articles hal-02639424v1
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Molecular profiling of patient-derived breast cancer xenografts.

Fabien Reyal , Charlotte Guyader , Charles Decraene , Carlo Lucchesi , Nathalie Auger et al.
Breast Cancer Research, 2012, 14 (1), pp.R11. ⟨10.1186/bcr3095⟩
Journal articles inserm-00675301v1
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SHH medulloblastoma in a young adult with a TCF4 germline pathogenic variation

Maud Blanluet , Julien Masliah-Planchon , Irina Giurgea , Franck Bielle , Élodie Girard et al.
Acta Neuropathologica, 2019, 137 (4), pp.675-678. ⟨10.1007/s00401-019-01983-4⟩
Journal articles hal-02347134v1
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A gene-expression profiling score for prediction of outcome in patients with follicular lymphoma: a retrospective training and validation analysis in three international cohorts

Sarah Huet , Bruno Tesson , Jean-Philippe Jais , Andrew Feldman , Laura Magnano et al.
Lancet Oncology, 2018, 19 (4), pp.549 - 561. ⟨10.1016/S1470-2045(18)30102-5⟩
Journal articles hal-01788996v1
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Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.

Alejandra Urrutia , Darragh Duffy , Vincent Rouilly , Céline Posseme , Raouf Djebali et al.
Cell Reports, 2016, 16 (10), pp.2777-91. ⟨10.1016/j.celrep.2016.08.011⟩
Journal articles pasteur-01367555v1
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Intratumor CMS Heterogeneity Impacts Patients prognosis in localized colon cancer

Laetitia Marisa , Yuna Blum , Julien Taieb , Mira Ayadi , Camilla Pilati et al.
Clinical Cancer Research, 2021, 27 (17), pp.4768-4780. ⟨10.1158/1078-0432.CCR-21-0529⟩
Journal articles inserm-03651990v1
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Designs and challenges for personalized medicine studies in oncology: focus on the SHIVA trial

Christophe Le Tourneau , Maud Kamal , Olivier Trédan , Jean-Pierre Delord , Mario Campone et al.
Targeted Oncology, 2012, 7 (4), pp.253-265. ⟨10.1007/s11523-012-0237-6⟩
Journal articles istex inserm-02294308v1
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The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

Morgane Sonia Thion , Cristovão Moreira Sousa , John Russel Mcguire , David Gentien , Pierre de La Grange et al.
EMBO Molecular Medicine, 2013, 5 (2), pp.309-325. ⟨10.1002/emmm.201201546⟩
Journal articles hal-03413278v1

A gene expression signature associated with metastatic cells in effusions of breast carcinoma patients

Virginie Dupont , David Gentien , Marine Oberkampf , Yann de Rycke , Nathalie Blin et al.
International Journal of Cancer, 2007, 121 (5), pp.1036-1046. ⟨10.1002/ijc.22775⟩
Journal articles pasteur-02872818v1
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Tyro3 Targeting as a Radiosensitizing Strategy in Bladder Cancer through Cell Cycle Dysregulation

Linda Silina , Florent Dufour , Audrey Rapinat , Cécile Reyes , David Gentien et al.
International Journal of Molecular Sciences, 2022, 23 (15), pp.8671. ⟨10.3390/ijms23158671⟩
Journal articles hal-03853939v1

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions

Houda Benhelli-Mokrani , Zeyni Mansuroglu , Alban Chauderlier , Benoit Albaud , David Gentien et al.
Nucleic Acids Research, 2018, ⟨10.1093/nar/gky929⟩
Journal articles hal-03093343v1