Search - Archive ouverte HAL Access content directly

Filter your results

9 Results
authFullName_s : Fabien Guidez
Image document

Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia

Carine Domenech , Loïc Maillard , Alix Rousseau , Fabien Guidez , Laurence Petit et al.
Stem Cell Reports, 2018, 11 (5), pp.1075-1091. ⟨10.1016/j.stemcr.2018.10.001⟩
Journal articles hal-01945976v1

An acetyltransferase assay for CREB-binding protein based on reverse phase–ultra-fast liquid chromatography of fluorescent histone H3 peptides

Romain Duval , Lauriane Fritsch , Linh-Chi Bui , Jérémy Berthelet , Fabien Guidez et al.
Analytical Biochemistry, 2015, 486, pp.35-37. ⟨10.1016/j.ab.2015.06.024⟩
Journal articles hal-03051625v1

PLZF Acetylation Levels Regulate NKT Cell Differentiation

Jihene Klibi , Claudine Joseph , Marc Delord , Aurelie Teissandier , Bruno Lucas et al.
Journal of Immunology, 2021, 207 (3), pp.809-823. ⟨10.4049/jimmunol.2001444⟩
Journal articles hal-03894507v1

Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor.

Lucia Altucci , Aurélie Rossin , Oliver Hirsch , Angela Nebbioso , Dominique Vitoux et al.
Cancer Research, 2005, 65 (19), pp.8754-65. ⟨10.1158/0008-5472.CAN-04-3569⟩
Journal articles hal-00187351v1
Image document

The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3)

Jérémy Berthelet , Christina Michail , Linh-Chi Bui , Louise Le Coadou , Valentina Sirri et al.
Molecular Pharmacology, 2021, 100 (3), pp.283 - 294. ⟨10.1124/molpharm.121.000303⟩
Journal articles hal-03435104v1
Image document

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

Petra Gorombei , Fabien Guidez , Saravanan Ganesan , Mathieu Chiquet , Andrea Pellagatti et al.
International Journal of Molecular Sciences, 2021, 22 (19), pp.10658. ⟨10.3390/ijms221910658⟩
Journal articles inserm-03945174v1
Image document

Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling

Romain Duval , Linh-Chi Bui , Cécile Mathieu , Qing Nian , Jérémy Berthelet et al.
Journal of Biological Chemistry, 2019, 294 (33), pp.12483-12494. ⟨10.1074/jbc.RA119.008666⟩
Journal articles hal-02358303v1
Image document

T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide

Qing Nian , Jeremy Berthelet , Wenchao Zhang , Linh-Chi Bui , Rongxing Liu et al.
Molecular Pharmacology, 2019, 96 (2), pp.297-306. ⟨10.1124/mol.119.116319⟩
Journal articles hal-03201556v1
Image document

Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues

Wenchao Zhang , Jérémy Berthelet , Christina Michail , Linh-Chi Bui , Panhong Gou et al.
Free Radical Biology and Medicine, 2021, 162, pp.27 - 37. ⟨10.1016/j.freeradbiomed.2020.11.027⟩
Journal articles hal-03492863v1