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Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia
Carine Domenech
,
Loïc Maillard
,
Alix Rousseau
,
Fabien Guidez
,
Laurence Petit
et al.
Journal articles
hal-01945976v1
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An acetyltransferase assay for CREB-binding protein based on reverse phase–ultra-fast liquid chromatography of fluorescent histone H3 peptides
Romain Duval
,
Lauriane Fritsch
,
Linh-Chi Bui
,
Jérémy Berthelet
,
Fabien Guidez
et al.
Journal articles
hal-03051625v1
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PLZF Acetylation Levels Regulate NKT Cell Differentiation
Jihene Klibi
,
Claudine Joseph
,
Marc Delord
,
Aurelie Teissandier
,
Bruno Lucas
et al.
Journal articles
hal-03894507v1
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Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor.
Lucia Altucci
,
Aurélie Rossin
,
Oliver Hirsch
,
Angela Nebbioso
,
Dominique Vitoux
et al.
Journal articles
hal-00187351v1
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The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3)
Jérémy Berthelet
,
Christina Michail
,
Linh-Chi Bui
,
Louise Le Coadou
,
Valentina Sirri
et al.
Journal articles
hal-03435104v1
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BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome
Petra Gorombei
,
Fabien Guidez
,
Saravanan Ganesan
,
Mathieu Chiquet
,
Andrea Pellagatti
et al.
Journal articles
inserm-03945174v1
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Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling
Romain Duval
,
Linh-Chi Bui
,
Cécile Mathieu
,
Qing Nian
,
Jérémy Berthelet
et al.
Journal articles
hal-02358303v1
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T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide
Qing Nian
,
Jeremy Berthelet
,
Wenchao Zhang
,
Linh-Chi Bui
,
Rongxing Liu
et al.
Journal articles
hal-03201556v1
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Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues
Wenchao Zhang
,
Jérémy Berthelet
,
Christina Michail
,
Linh-Chi Bui
,
Panhong Gou
et al.
Journal articles
hal-03492863v1
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